![Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them](/docs/US/2005-11-17/US20050256151A1/abs.jpg.600x600.jpg)
- 专利标题： Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
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申请号： US11020793申请日： 2004-12-23
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公开(公告)号： US20050256151A1公开(公告)日： 2005-11-17
- 发明人: Barbara Salom , Matteo D'Anello , Maria Brasca , Patrizia Giordano , Katia Martina , Francesco Angelucci , Frederick Brookfield , William Trigg , Edward Boyd , Jonathan Larard
- 申请人： Barbara Salom , Matteo D'Anello , Maria Brasca , Patrizia Giordano , Katia Martina , Francesco Angelucci , Frederick Brookfield , William Trigg , Edward Boyd , Jonathan Larard
- 申请人地址： IT Milano
- 专利权人： Pharmacia Italia S.p.A.
- 当前专利权人： Pharmacia Italia S.p.A.
- 当前专利权人地址： IT Milano
- 优先权： GB0330043.1 20031224
- 主分类号： C07D471/04
- IPC分类号： C07D471/04 ; G01N33/53 ; A61K31/4745 ; C07D471/02
![Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them](/abs-image/US/2005/11/17/US20050256151A1/abs.jpg.150x150.jpg)
摘要：
Compounds which are pyrrolo[2,3-b]pyridine derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders; also disclosed is a process under SPS conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.