发明申请
- 专利标题： Nitrogen-containing compounds
- 专利标题（中）： 含氮化合物
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申请号： US10525061申请日： 2003-08-18
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公开(公告)号： US20050256166A1公开(公告)日： 2005-11-17
- 发明人: Hisao Nakai , Takashi Kondo , Susumu Yamamoto
- 申请人： Hisao Nakai , Takashi Kondo , Susumu Yamamoto
- 优先权： JP2002-238673 20020819
- 国际申请： PCT/JP03/10401 WO 20030818
- 主分类号： A61K31/4025
- IPC分类号： A61K31/4025 ; A61K31/403 ; A61K31/404 ; A61K31/4245 ; A61K31/427 ; A61K31/428 ; A61K31/429 ; A61K31/437 ; A61K31/438 ; A61K31/4439 ; A61K31/454 ; A61K31/5377 ; A61K31/541 ; A61P3/04 ; A61P3/10 ; A61P13/08 ; A61P17/00 ; A61P35/04 ; A61P37/00 ; A61P37/04 ; A61P43/00 ; C07D207/16 ; C07D207/22 ; C07D277/06 ; C07D277/56 ; C07D401/14 ; C07D403/06 ; C07D405/14 ; C07D413/14 ; C07D417/06 ; C07D417/14 ; C07D417/02
摘要：
A compound represented by formula (I); wherein ring A represents a nitrogen containing heterocyclic ring, ring B represents 5-membered heterocyclic ring which may have substituents, R represents a hydrogen atom or cyano and the other symbols represent as described in the specification; or a salt thereof. The compound represented by formula (I) has an inhibitory activity of DPP-IV, and therefore is useful as a preventive and/or treatment agent for type 2 diabetes mellitus, obesity, autoimmune disease, cancer metastasis, AIDS virus infection, dermatosis, prostatic hypertrophy and the like
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