发明申请
- 专利标题: Formulations of anthraquinone derivatives
- 专利标题(中): 蒽醌衍生物的配方
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申请号: US10507483申请日: 2003-03-17
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公开(公告)号: US20050256188A1公开(公告)日: 2005-11-17
- 发明人: William Denny , Laurence Patterson , Gavin Halbert , Steven Ford
- 申请人: William Denny , Laurence Patterson , Gavin Halbert , Steven Ford
- 优先权: GB0206255.2 20020315
- 国际申请: PCT/GB03/01110 WO 20030317
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K31/21 ; A61K47/02 ; A61K47/12 ; C07C225/34 ; C07C225/36 ; C07C291/04
摘要:
A compound of formula (I): in which A is a C alkylene group with a chain length between NH and N(O)R′R″ of at least 2 carbon atoms and R′ and R″ are each separately selected from C1-4 alkyl groups and C2-4 hydroxyalkyl and C2-4 dihydroxyalkyl groups, or R′ and R″ together are a C2-6 alkylene group, is formulated so that upon dissolution in aqueous solution the pH of the solution is in the range of 5 to 9. The compound may be in the form of salt with a physiologically acceptable acid having a pKa in the range of −3.0 (minus 3.0) to 9.0.
公开/授权文献
- US07074835B2 Formulations of anthraquinone derivatives 公开/授权日:2006-07-11
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