发明申请
- 专利标题: Benzoquinone ansamycins
- 专利标题(中): 苯并醌安莎霉素
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申请号: US11056470申请日: 2005-02-11
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公开(公告)号: US20050261263A1公开(公告)日: 2005-11-24
- 发明人: Daniel Santi , David Myles , Zong-Qiang Tian , C. Hutchinson , Robert Johnson , Yi-Qing Zhou , Li Feng
- 申请人: Daniel Santi , David Myles , Zong-Qiang Tian , C. Hutchinson , Robert Johnson , Yi-Qing Zhou , Li Feng
- 主分类号: C07D225/06
- IPC分类号: C07D225/06 ; C07D491/08 ; A61K31/5377 ; A61K31/33 ; A61K31/4178 ; A61K31/452 ; A61K31/496
摘要:
The invention relates to benzoquinone ansamycin analogs useful for the treatment of cancer and other diseases or conditions characterized by undesired cellular proliferation or hyperproliferation. Therapies involving the administration of such benzoquinone ansamycin analogs, optionally in combination with an inhibitor of an HSP90 client protein, are useful to treat cancer and non-cancerous disease conditions.
公开/授权文献
- US07405208B2 Benzoquinone ansamycins 公开/授权日:2008-07-29
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