发明申请
US20050272075A1 Novel methods for quantification of microRNAs and small interfering RNAs
有权
用于定量微小RNA和小干扰RNA的新方法
- 专利标题： Novel methods for quantification of microRNAs and small interfering RNAs
- 专利标题（中）： 用于定量微小RNA和小干扰RNA的新方法
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申请号： US11100897申请日： 2005-04-07
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公开(公告)号： US20050272075A1公开(公告)日： 2005-12-08
- 发明人: Nana Jacobsen , Lars Kongsbak , Sakari Kauppinen , Soren Echwald , Peter Mouritzen , Peter Nielsen , Mikkel Norholm
- 申请人： Nana Jacobsen , Lars Kongsbak , Sakari Kauppinen , Soren Echwald , Peter Mouritzen , Peter Nielsen , Mikkel Norholm
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice variants, as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification as well as monitoring the expression of deoxy nucleic acids.