发明申请
US20050282232A1 Compositions and methods for modulating c-Rel-dependent cytokine production
审中-公开
用于调节c-Rel依赖性细胞因子产生的组合物和方法
- 专利标题： Compositions and methods for modulating c-Rel-dependent cytokine production
- 专利标题（中）： 用于调节c-Rel依赖性细胞因子产生的组合物和方法
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申请号： US10986553申请日： 2004-11-10
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公开(公告)号： US20050282232A1公开(公告)日： 2005-12-22
- 发明人: Rongzhen Lu , James Barsoum , Yumiko Wada
- 申请人： Rongzhen Lu , James Barsoum , Yumiko Wada
- 主分类号： A61K
- IPC分类号： A61K20060101 ; G01N33/50 ; G01N33/53 ; G01N33/567
摘要：
The present invention is directed to compositions and methods for modulating c-Rel-dependent cytokine production without materially altering the level of expression of NFκB and/or the amount of IκB. The present invention is also directed to screening for modulators of c-Rel activity as determined by assaying for altered subcellular localization of c-Rel but where the level of expression of NFκB and/or the amount of IκB is materially unaltered.
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