发明申请
US20050282853A1 Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8,-tetrahydro-imidazo[1,2,-a]pyridines as antiprotozoal agents
有权
新型二环咪唑并[1,2-a]吡啶和5,6,7,8-四氢 - 咪唑并[1,2-a]吡啶作为抗原虫剂
![Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8,-tetrahydro-imidazo[1,2,-a]pyridines as antiprotozoal agents](/docs/US/2005-12-22/US20050282853A1/abs.jpg.600x600.jpg)
- 专利标题： Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8,-tetrahydro-imidazo[1,2,-a]pyridines as antiprotozoal agents
- 专利标题（中）： 新型二环咪唑并[1,2-a]吡啶和5,6,7,8-四氢 - 咪唑并[1,2-a]吡啶作为抗原虫剂
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申请号： US11074565申请日： 2005-03-08
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公开(公告)号： US20050282853A1公开(公告)日： 2005-12-22
- 发明人: David Boykin , Richard Tidwell , W. Wilson , Mohamed Ismail
- 申请人： David Boykin , Richard Tidwell , W. Wilson , Mohamed Ismail
- 主分类号： A61K31/4745
- IPC分类号： A61K31/4745 ; C07D471/02 ; C07D471/04
![Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8,-tetrahydro-imidazo[1,2,-a]pyridines as antiprotozoal agents](/abs-image/US/2005/12/22/US20050282853A1/abs.jpg.150x150.jpg)
摘要：
A method for treating a microbial infection, including an infection from a protozoan pathogen, such as Trypanosoma brucei rhodesiense and Plasmodium falciparum, in a subject in need thereof by administering to the subject an effective amount of a dicationic imidazopyridine compound or a dicationic tetrahydro-imidazopyridine compound. Processes for synthesizing dicationic imidazopyridines and dicationic tetrahydro-imidazopyridines and the novel dicationic imidazopyridine and dicationic tetrahydro-imidazopyridine compounds themselves.
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