发明申请
US20050287117A1 Vaccine enhancing the protective immunity to hepatitis c virus using plasmid dna and recombinant adenovirus
失效
疫苗使用质粒dna和重组腺病毒增强丙型肝炎病毒的保护性免疫力
- 专利标题： Vaccine enhancing the protective immunity to hepatitis c virus using plasmid dna and recombinant adenovirus
- 专利标题（中）： 疫苗使用质粒dna和重组腺病毒增强丙型肝炎病毒的保护性免疫力
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申请号： US10528644申请日： 2003-09-24
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公开(公告)号： US20050287117A1公开(公告)日： 2005-12-29
- 发明人: Young Sung , Young Sung , Jin-won Youn , Se-Hwan Yang , Su-Hyung Park , Chang Lee
- 申请人： Young Sung , Young Sung , Jin-won Youn , Se-Hwan Yang , Su-Hyung Park , Chang Lee
- 申请人地址： KR Seoul 150-889 KR Gyeongsangbuk-do 790-784 KR Seoul 130-823 KR Kyunggi-do 462-807 KR Gyeongsangbuk-do 790-704
- 专利权人： Genexine Inc.,Postech Foundation,Dong-A Pharm. Co., Ltd.,Daewood Co., Ltd,Posco
- 当前专利权人： Genexine Inc.,Postech Foundation,Dong-A Pharm. Co., Ltd.,Daewood Co., Ltd,Posco
- 当前专利权人地址： KR Seoul 150-889 KR Gyeongsangbuk-do 790-784 KR Seoul 130-823 KR Kyunggi-do 462-807 KR Gyeongsangbuk-do 790-704
- 优先权： KR10-2002-0058712 20020927; KR10-2002-0068496 20021106
- 国际申请： PCT/KR03/01951 WO 20030924
- 主分类号： A61K39/29
- IPC分类号： A61K39/29 ; A61K39/12 ; A61K48/00
摘要：
The present invention relates to a vaccine enhancing the protective immunity to Hepatitis C virus using plasmid DNA and recombinant adenovirus, more particularly to a vaccine consisting of Δcore-E1-E2 expressing DNA vaccine, nonstructural protein NS3 and NS4 expressing DNA vaccine, nonstructural protein NS5 expressing DNA vaccine and recombinant adenovirus vaccine, and method for administration of the vaccine by priming with the DNA vaccines described above and boosting with the recombinant adenovirus vaccine thereby enhancing the protective immunity to Hepatitis C virus.