发明申请
US20060003012A9 Preparation of submicron solid particle suspensions by sonication of multiphase systems
审中-公开
通过超声处理多相体系制备亚微米固体颗粒悬浮液
- 专利标题： Preparation of submicron solid particle suspensions by sonication of multiphase systems
- 专利标题（中）： 通过超声处理多相体系制备亚微米固体颗粒悬浮液
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申请号： US09964273申请日： 2001-09-26
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公开(公告)号： US20060003012A9公开(公告)日： 2006-01-05
- 发明人: Sean Brynjelsen , Shmuel Sternberg , Andy Dunham
- 申请人： Sean Brynjelsen , Shmuel Sternberg , Andy Dunham
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; B01J13/02 ; B01J13/04
摘要：
The present invention provides a method for preparing submicron-sized particles. The method includes the steps of: (1) providing a multiphase system having an organic phase and an aqueous phase, the organic phase having a pharmaceutically effective compound therein; and (2) sonicating the system to evaporate a portion of the organic phase to cause precipitation of the compound in the aqueous phase and having an average effective particle size of less than about 2 m.
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