The individual performance of various transistors is optimized by tailoring the thickness of the gate oxide layer to a particular operating voltage. Embodiments include forming transistors with different gate oxide thicknesses by initially depositing one or more gate oxide layers with intermediate etching to remove the deposited oxide from active regions wherein transistors with relatively thinner gate oxides are to be formed, and then implementing one or more thermal oxidation steps. Embodiments include forming semiconductor devices comprising transistors with two different gate oxide thicknesses by initially depositing an oxide film, selectively removing the deposited oxide film from active areas in which low voltage transistors having a relatively thin gate oxide are to be formed, and then implementing thermal oxidation.