发明申请
US20060004082A1 6H-thieno'2, 3-b!pyrrole derivatives as antagonists of gonadotropin releasing hormone (gnrh)
有权
6H-thieno'2,3-b！吡咯衍生物作为促性腺激素释放激素（gnrh）的拮抗剂
- 专利标题： 6H-thieno'2, 3-b!pyrrole derivatives as antagonists of gonadotropin releasing hormone (gnrh)
- 专利标题（中）： 6H-thieno'2,3-b！吡咯衍生物作为促性腺激素释放激素（gnrh）的拮抗剂
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申请号： US10524978申请日： 2003-08-19
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公开(公告)号： US20060004082A1公开(公告)日： 2006-01-05
- 发明人: Kevin Foote , Zbigniew Matusiak , Alexander Dossetter , Jean Arnould , Maryannick Lamorlette , Benedicte Delouvrie , Annie Hamon
- 申请人： Kevin Foote , Zbigniew Matusiak , Alexander Dossetter , Jean Arnould , Maryannick Lamorlette , Benedicte Delouvrie , Annie Hamon
- 申请人地址： SE Sodertalje SE-151 85
- 专利权人： AstraZeneca
- 当前专利权人： AstraZeneca
- 当前专利权人地址： SE Sodertalje SE-151 85
- 优先权： EP02292074.8 20020821
- 国际申请： PCT/GB03/03631 WO 20030819
- 主分类号： A61K31/407
- IPC分类号： A61K31/407 ; C07D498/02
摘要：
The invention relates to a group of novel thieno-pyrrole compounds of Formula (1): wherein: R1, R2, R3, R4 and R5 are as defined in the specification, which are useful as gonadotrophin releasing hormone antagonists. The invention also relates to pharmaceutical formulations of said compounds, methods of treatment using said compounds and to processes for the preparation of said compounds.
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