发明申请
- 专利标题： Naphthylene derivatives as cytochrome P450 inhibitors
- 专利标题（中）： 萘衍生物作为细胞色素P450抑制剂
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申请号： US10889520申请日： 2004-07-12
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公开(公告)号： US20060009645A1公开(公告)日： 2006-01-12
- 发明人: Vanessa Smith , Anthony Nigro , Mark Mulvihill , Cara Cesario , Patricia Beck , Arlindo Castelhano
- 申请人： Vanessa Smith , Anthony Nigro , Mark Mulvihill , Cara Cesario , Patricia Beck , Arlindo Castelhano
- 主分类号： C07D249/08
- IPC分类号： C07D249/08 ; C07D233/61
摘要：
Compounds of the formula and pharmaceutically acceptable salts thereof, wherein n1, n2, n3, n4, G1, Q1, Z, R1, R2, R3, R4a, R4b, R5a, and R5b are defined herein, inhibit the cytochrome P450RAI enzyme and are useful for the treatment and/or prevention of various diseases and conditions which respond to treatment by retinoids and by naturally occurring retinoic acid.
公开/授权文献
- US07662844B2 Naphthylene derivatives as cytochrome P450 inhibitors 公开/授权日：2010-02-16
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