发明申请
- 专利标题: LIGAND-CONTROLLED REGULATION OF ENDOGENOUS GENE EXPRESSION
- 专利标题(中): 内源基因表达的配体控制调控
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申请号: US10456444申请日: 2003-06-05
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公开(公告)号: US20060014286A1公开(公告)日: 2006-01-19
- 发明人: George Cox , Casey Case , Stephen Eisenberg , Eric Jarvis , Sharon Spratt
- 申请人: George Cox , Casey Case , Stephen Eisenberg , Eric Jarvis , Sharon Spratt
- 主分类号: C12N15/85
- IPC分类号: C12N15/85 ; A61K31/57
摘要:
Disclosed herein are compositions comprising an engineered zinc finger protein and a nuclear hormone receptor transcriptional control domain, polynucleotides encoding one or more components of the compositions, methods of making the compositions and methods of using these compositions, for example to modulate gene expression and/or to generate transgenic plants or animals.
公开/授权文献
- US07070934B2 Ligand-controlled regulation of endogenous gene expression 公开/授权日:2006-07-04
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