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公开(公告)号:US20060078878A1
公开(公告)日:2006-04-13
申请号:US10222614
申请日:2002-08-15
申请人: George Cox , Casey Case , Stephen Eisenberg , Eric Jarvis , Sharon Spratt
发明人: George Cox , Casey Case , Stephen Eisenberg , Eric Jarvis , Sharon Spratt
CPC分类号: A01K67/0275 , A01K2217/05 , A61K48/00 , A61K48/005 , C07K14/47 , C07K14/52 , C07K2319/00 , C07K2319/71 , C07K2319/81 , C12N15/63 , C12N15/67 , C12N15/8216 , C12N15/85 , C12N2830/002 , C12N2830/005 , C12N2830/008 , C12N2830/85 , C12Q1/66 , C12Q1/6897 , G01N33/5091
摘要: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
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公开(公告)号:US20060281704A1
公开(公告)日:2006-12-14
申请号:US11505775
申请日:2006-08-17
申请人: George Cox , Casey Case , Stephen Eisenberg , Eric Jarvis , Sharon Spratt
发明人: George Cox , Casey Case , Stephen Eisenberg , Eric Jarvis , Sharon Spratt
IPC分类号: A61K48/00
CPC分类号: A01K67/0275 , A01K2217/05 , A61K48/00 , A61K48/005 , C07K14/47 , C07K14/52 , C07K2319/00 , C07K2319/71 , C07K2319/81 , C12N15/63 , C12N15/67 , C12N15/8216 , C12N15/85 , C12N2830/002 , C12N2830/005 , C12N2830/008 , C12N2830/85 , C12Q1/66 , C12Q1/6897 , G01N33/5091
摘要: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
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公开(公告)号:US20060276427A1
公开(公告)日:2006-12-07
申请号:US11505044
申请日:2006-08-16
申请人: George Cox , Casey Case , Stephen Eisenberg , Eric Jarvis , Sharon Spratt
发明人: George Cox , Casey Case , Stephen Eisenberg , Eric Jarvis , Sharon Spratt
CPC分类号: A01K67/0275 , A01K2217/05 , A61K48/00 , A61K48/005 , C07K14/47 , C07K14/52 , C07K2319/00 , C07K2319/71 , C07K2319/81 , C12N15/63 , C12N15/67 , C12N15/8216 , C12N15/85 , C12N2830/002 , C12N2830/005 , C12N2830/008 , C12N2830/85 , C12Q1/66 , C12Q1/6897 , G01N33/5091
摘要: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
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公开(公告)号:US20060014286A1
公开(公告)日:2006-01-19
申请号:US10456444
申请日:2003-06-05
申请人: George Cox , Casey Case , Stephen Eisenberg , Eric Jarvis , Sharon Spratt
发明人: George Cox , Casey Case , Stephen Eisenberg , Eric Jarvis , Sharon Spratt
CPC分类号: A61K31/57
摘要: Disclosed herein are compositions comprising an engineered zinc finger protein and a nuclear hormone receptor transcriptional control domain, polynucleotides encoding one or more components of the compositions, methods of making the compositions and methods of using these compositions, for example to modulate gene expression and/or to generate transgenic plants or animals.
摘要翻译: 本文公开了包含工程化锌指蛋白和核激素受体转录控制结构域的组合物,编码组合物的一种或多种组分的多核苷酸,制备组合物的方法和使用这些组合物的方法,例如调节基因表达和/或 以产生转基因植物或动物。
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5.Regulation of endogenous gene expression in cells using zinc finger proteins 审中-公开
标题翻译: 使用锌指蛋白调节细胞内源性基因表达公开(公告)号:US20050215502A1
公开(公告)日:2005-09-29
申请号:US10984304
申请日:2004-11-09
申请人: George Cox , Casey Case , Stephen Eisenberg , Eric Jarvis , Sharon Spratt
发明人: George Cox , Casey Case , Stephen Eisenberg , Eric Jarvis , Sharon Spratt
IPC分类号: C12N15/09 , A61K31/711 , A61K35/76 , A61K38/16 , A61K48/00 , A61P7/00 , A61P7/06 , A61P9/00 , A61P9/10 , A61P11/00 , A61P17/06 , A61P19/02 , A61P21/00 , A61P21/04 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P35/00 , A61P37/00 , C07K14/46 , C07K14/47 , C07K14/52 , C12N5/10 , C12N9/64 , C12N15/12 , C12N15/63 , C12N15/67 , C12N15/82 , C12N15/85 , C12P21/04 , C12Q1/68
CPC分类号: A01K67/0275 , A01K2217/05 , A61K48/00 , A61K48/005 , C07K14/47 , C07K14/52 , C07K2319/00 , C07K2319/71 , C07K2319/81 , C12N15/63 , C12N15/67 , C12N15/8216 , C12N15/85 , C12N2830/002 , C12N2830/005 , C12N2830/008 , C12N2830/85 , C12Q1/66 , C12Q1/6897 , G01N33/5091
摘要: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
摘要翻译: 本发明提供了使用重组锌指蛋白调节内源细胞基因表达的方法。
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公开(公告)号:US20050130304A1
公开(公告)日:2005-06-16
申请号:US10986583
申请日:2004-11-12
申请人: George Cox , Casey Case , Stephen Eisenberg , Eric Jarvis , Sharon Spratt
发明人: George Cox , Casey Case , Stephen Eisenberg , Eric Jarvis , Sharon Spratt
IPC分类号: C12N15/09 , A61K31/711 , A61K35/76 , A61K38/16 , A61K48/00 , A61P7/00 , A61P7/06 , A61P9/00 , A61P9/10 , A61P11/00 , A61P17/06 , A61P19/02 , A61P21/00 , A61P21/04 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P35/00 , A61P37/00 , C07K14/46 , C07K14/47 , C07K14/52 , C12N5/10 , C12N9/64 , C12N15/12 , C12N15/63 , C12N15/67 , C12N15/82 , C12N15/85 , C12P21/04 , C12Q1/68 , C12N5/08 , C12N5/04
CPC分类号: A01K67/0275 , A01K2217/05 , A61K48/00 , A61K48/005 , C07K14/47 , C07K14/52 , C07K2319/00 , C07K2319/71 , C07K2319/81 , C12N15/63 , C12N15/67 , C12N15/8216 , C12N15/85 , C12N2830/002 , C12N2830/005 , C12N2830/008 , C12N2830/85 , C12Q1/66 , C12Q1/6897 , G01N33/5091
摘要: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
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