- 专利标题: Heparin prodrugs and drug delivery stents formed therefrom
-
申请号: US11228420申请日: 2005-09-15
-
公开(公告)号: US20060014720A1公开(公告)日: 2006-01-19
- 发明人: Syed Hossainy , Ni Ding
- 申请人: Syed Hossainy , Ni Ding
- 专利权人: Advanced Cardiovascular Systems, Inc.
- 当前专利权人: Advanced Cardiovascular Systems, Inc.
- 主分类号: A61K31/727
- IPC分类号: A61K31/727 ; A61K38/17 ; C08B37/10
摘要:
A prodrug comprising a heparin and a drug is provided. The prodrug can be used to form a coating on a medical device. The prodrug can also be used with a polymeric material to form a coating on a medical device. The polymeric material can be a hydrophobic polymer, a hydrophilic polymer, a non-fouling polymer, or combinations thereof. The medical device can be implanted in a human being for the treatment of a disease such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.
公开/授权文献
- US07396541B2 Heparin prodrugs and drug delivery stents formed therefrom 公开/授权日:2008-07-08