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公开(公告)号：US20060198897A1
公开(公告)日：2006-09-07
申请号：US11213288
申请日：2005-08-26
Applicant: Stephen Pacetti , Eugene Michal , Syed Hossainy , Ni Ding , Wouter Roorda
Inventor： Stephen Pacetti , Eugene Michal , Syed Hossainy , Ni Ding , Wouter Roorda
CPC classification number: A61K31/727 , A61K31/728 , A61K31/737 , A61L31/10 , C08L89/00
Abstract: Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed.
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公开(公告)号：US20060018944A1
公开(公告)日：2006-01-26
申请号：US11213290
申请日：2005-08-26
Applicant: Stephen Pacetti , Eugene Michal , Syed Hossainy , Ni Ding , Wouter Roorda
Inventor： Stephen Pacetti , Eugene Michal , Syed Hossainy , Ni Ding , Wouter Roorda
IPC: A61K31/727 , A61F13/00
CPC classification number: A61K31/727 , A61K31/728 , A61K31/737 , A61L31/10 , C08L89/00
Abstract: Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed.
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3.发明申请公开(公告)号：US20060246209A1
公开(公告)日：2006-11-02
申请号：US11395014
申请日：2006-03-31
Applicant: Andrew McNiven , Thomas Esbeck , Ni Ding , Stephen Pacetti , Syed Hossainy
Inventor： Andrew McNiven , Thomas Esbeck , Ni Ding , Stephen Pacetti , Syed Hossainy
IPC: A61L33/00
CPC classification number: A61L31/10 , A61L31/16 , A61L2300/602 , B05D3/107
Abstract: A method for modifying a polymeric coating on an implantable medical device, such as a stent, is disclosed. The method includes application of a fluid to a wet or dry polymeric coating with and without drugs.
Abstract translation: 公开了一种用于修改可植入医疗装置（例如支架）上的聚合物涂层的方法。 该方法包括将液体施用于具有和不具有药物的湿或干燥聚合物涂层。
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公开(公告)号：US20060014720A1
公开(公告)日：2006-01-19
申请号：US11228420
申请日：2005-09-15
Applicant: Syed Hossainy , Ni Ding
Inventor： Syed Hossainy , Ni Ding
IPC: A61K31/727 , A61K38/17 , C08B37/10
CPC classification number: A61K31/727 , A61K47/61 , A61L31/10 , A61L31/16 , A61L2300/236 , A61L2300/606 , A61L2300/80 , C08B37/0075 , C09D105/10
Abstract: A prodrug comprising a heparin and a drug is provided. The prodrug can be used to form a coating on a medical device. The prodrug can also be used with a polymeric material to form a coating on a medical device. The polymeric material can be a hydrophobic polymer, a hydrophilic polymer, a non-fouling polymer, or combinations thereof. The medical device can be implanted in a human being for the treatment of a disease such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.
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公开(公告)号：US20050208093A1
公开(公告)日：2005-09-22
申请号：US10807362
申请日：2004-03-22
Applicant: Thierry Glauser , Stephen Pacetti , Syed Hossainy , Ni Ding
Inventor： Thierry Glauser , Stephen Pacetti , Syed Hossainy , Ni Ding
IPC: A61L27/34 , A61L31/10 , C08G63/91 , A61K31/785 , A61K31/765 , C08G63/48
CPC classification number: A61L31/10 , A61L27/34 , A61L31/148 , A61L31/16 , A61L33/0011 , A61L33/08 , A61L2300/40 , A61L2300/42 , A61L2300/604 , A61L2300/606 , A61L2400/18 , C08L33/14
Abstract: A polymer comprising phospholipid moieties and a biocompatible polymer backbone, a composition comprising the polymer and optionally a bioactive agent, an implantable devices such as a DES comprising thereon a coating comprising the polymer and optionally a bioactive agent, and a method of using the device for the treatment of a disorder in a human being are provided.
Abstract translation: 包含磷脂部分和生物相容性聚合物骨架的聚合物，包含聚合物和任选的生物活性剂的组合物，可植入装置，例如包含其上的包含聚合物和任选的生物活性剂的涂层的DES，以及使用该装置的方法 提供了人类疾病的治疗。
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Patent Agency Ranking
公开(公告)号：US20050106203A1
公开(公告)日：2005-05-19
申请号：US10176504
申请日：2002-06-21
Applicant: Wouter Roorda , Ni Ding , Stephen Pacetti , Eugene Michal , Ashok Shah , Syed Hossainy
Inventor： Wouter Roorda , Ni Ding , Stephen Pacetti , Eugene Michal , Ashok Shah , Syed Hossainy
CPC classification number: A61L31/16 , A61L31/10 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/608 , A61L2420/08 , C08L33/10 , C08L33/06
Abstract: A coating for a medical device, particularly for a drug eluting stent, is described. The coating can include a polyacrylate, a blend of polyacrylates, or a blend of the polyacrylate with other polymers, for example, poly(ethylene-co-vinyl alcohol).
Abstract translation: 描述了用于医疗装置的涂层，特别是用于药物洗脱支架的涂层。 涂层可以包括聚丙烯酸酯，聚丙烯酸酯的共混物或聚丙烯酸酯与其它聚合物的共混物，例如聚（乙烯 - 共 - 乙烯醇）。
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公开(公告)号：US20070059434A1
公开(公告)日：2007-03-15
申请号：US11592632
申请日：2006-11-02
Applicant: Wouter Roorda , Syed Hossainy , Ni Ding , Fuh-Wei Tang , Stephen Pacetti
Inventor： Wouter Roorda , Syed Hossainy , Ni Ding , Fuh-Wei Tang , Stephen Pacetti
CPC classification number: A61L31/10 , A61L31/16 , A61L2300/416 , A61L2420/02 , A61L2420/08
Abstract: A method of coating an implantable medical device, such as a stent, is disclosed. The method includes applying a formulation on a first polymer layer containing a therapeutic substance to form a second layer. The formulation can contain a highly hydrophobic polymer or a solvent which is a poor solvent for the drug or the polymer of the first layer. The formulation can have a low surface tension value or a high Weber number value.
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公开(公告)号：US20060002974A1
公开(公告)日：2006-01-05
申请号：US11212376
申请日：2005-08-26
Applicant: Stephen Pacetti , Eugene Michal , Syed Hossainy , Ni Ding , Wouter Roorda
Inventor： Stephen Pacetti , Eugene Michal , Syed Hossainy , Ni Ding , Wouter Roorda
IPC: A61K31/737 , A61K31/727 , A61K31/728 , A61F2/00
CPC classification number: A61K31/727 , A61K31/728 , A61K31/737 , A61L31/10 , C08L89/00
Abstract: Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed.
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公开(公告)号：US08747385B2
公开(公告)日：2014-06-10
申请号：US13468956
申请日：2012-05-10
Applicant: Eugene T. Michal , Evgenia Mandrusov , Charles D. Claude , Ni Ding , Murthy Simhambhatla , Syed Faiyez Ahmed Hossainy , Srinivasan Sridharan , Paul Consigny
Inventor： Eugene T. Michal , Evgenia Mandrusov , Charles D. Claude , Ni Ding , Murthy Simhambhatla , Syed Faiyez Ahmed Hossainy , Srinivasan Sridharan , Paul Consigny
IPC: A61M31/00
CPC classification number: A61K9/0019 , A61K9/0024 , A61K31/7088
Abstract: Methods, devices, kits and compositions to treat a myocardial infarction. In one embodiment, the method includes the prevention of remodeling of the infarct zone of the ventricle. In other embodiments, the method includes the introduction of structurally reinforcing agents. In other embodiments, agents are introduced into a ventricle to increase compliance of the ventricle. In an alternative embodiment, the prevention of remodeling includes the prevention of thinning of the ventricular infarct zone. In another embodiment, the prevention of remodeling and thinning of the infarct zone involves the cross-linking of collagen and prevention of collagen slipping. In other embodiments, the structurally reinforcing agent may be accompanied by other therapeutic agents. These agents may include but are not limited to pro-fibroblastic and angiogenic agents.
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公开(公告)号：US08394446B2
公开(公告)日：2013-03-12
申请号：US12485756
申请日：2009-06-16
Applicant: Ni Ding
Inventor： Ni Ding
IPC: B05D3/00
CPC classification number: A61F2/82 , A61L31/10 , A61L31/143 , B65B55/00 , B65D1/00 , B65D3/00 , B65D77/04 , C08K5/13
Abstract: Methods of incorporating an antioxidant into a medical device including a polymer are described, and methods of packaging medical devices.
Abstract translation: 本发明描述了将抗氧化剂并入包括聚合物的医疗装置中的方法，以及包装医疗装置的方法。
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