发明申请
US20060025404A1 Substituted piperazines,(1,4) diaszepines, and 2,5-diazabicyclo (2.2.1)iieptanes as histamine h1 and/or h3 antagonists or histamine h3 reverse antagonists
失效
作为组胺h1和/或h3拮抗剂或组胺h3反向拮抗剂的取代的哌嗪，（1,4）二氮杂和2,5-二氮杂双环（2.2.1）
- 专利标题： Substituted piperazines,(1,4) diaszepines, and 2,5-diazabicyclo (2.2.1)iieptanes as histamine h1 and/or h3 antagonists or histamine h3 reverse antagonists
- 专利标题（中）： 作为组胺h1和/或h3拮抗剂或组胺h3反向拮抗剂的取代的哌嗪，（1,4）二氮杂和2,5-二氮杂双环（2.2.1）
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申请号： US10531758申请日： 2003-10-14
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公开(公告)号： US20060025404A1公开(公告)日： 2006-02-02
- 发明人: Rachel Ancliff , Colin Eldred , Yvonne Fogden , Ashley Hancock , Thomas Heightman , Heather Hobbs , Simon Hodgson , Matthew Lindon , David Wilson
- 申请人： Rachel Ancliff , Colin Eldred , Yvonne Fogden , Ashley Hancock , Thomas Heightman , Heather Hobbs , Simon Hodgson , Matthew Lindon , David Wilson
- 优先权： GB0224084,4 20021016
- 国际申请： PCT/EP03/11423 WO 20031014
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; A61K31/496
摘要：
The present invention relates to novel piperazine and azepine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurodegenerative disorders including Alzheimer's disease.
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