Invention Application
US20060025404A1 Substituted piperazines,(1,4) diaszepines, and 2,5-diazabicyclo (2.2.1)iieptanes as histamine h1 and/or h3 antagonists or histamine h3 reverse antagonists
失效
作为组胺h1和/或h3拮抗剂或组胺h3反向拮抗剂的取代的哌嗪，（1,4）二氮杂和2,5-二氮杂双环（2.2.1）
- Patent Title: Substituted piperazines,(1,4) diaszepines, and 2,5-diazabicyclo (2.2.1)iieptanes as histamine h1 and/or h3 antagonists or histamine h3 reverse antagonists
- Patent Title (中): 作为组胺h1和/或h3拮抗剂或组胺h3反向拮抗剂的取代的哌嗪，（1,4）二氮杂和2,5-二氮杂双环（2.2.1）
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Application No.: US10531758Application Date: 2003-10-14
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Publication No.: US20060025404A1Publication Date: 2006-02-02
- Inventor: Rachel Ancliff , Colin Eldred , Yvonne Fogden , Ashley Hancock , Thomas Heightman , Heather Hobbs , Simon Hodgson , Matthew Lindon , David Wilson
- Applicant: Rachel Ancliff , Colin Eldred , Yvonne Fogden , Ashley Hancock , Thomas Heightman , Heather Hobbs , Simon Hodgson , Matthew Lindon , David Wilson
- Priority: GB0224084,4 20021016
- International Application: PCT/EP03/11423 WO 20031014
- Main IPC: A61K31/551
- IPC: A61K31/551 ; A61K31/496
Abstract:
The present invention relates to novel piperazine and azepine derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurodegenerative disorders including Alzheimer's disease.
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