- 专利标题： Method of improved diuresis in individuals with impaired renal function
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申请号： US11248905申请日： 2005-10-11
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公开(公告)号： US20060035911A1公开(公告)日： 2006-02-16
- 发明人: Kenneth Widder , Lauren Otsuki , Howard Dittrich , Scott Thomson , Roland Blantz
- 申请人： Kenneth Widder , Lauren Otsuki , Howard Dittrich , Scott Thomson , Roland Blantz
- 主分类号： A61K31/549
- IPC分类号： A61K31/549 ; A61K31/522
摘要：
Disclosed is a pharmaceutical composition comprising a therapeutically effective amount of KW-3902, or a salt, ester, amide, metabolite, or prodrug thereof, and a non-adenosine modifying diuretic. Also disclosed are methods of inducing a diuretic effect in an animal comprising the step of administering a therapeutically effective amount of KW-3902, or a salt, ester, amide, metabolite, or prodrug thereof, in combination with second pharmaceutical composition capable of inducing a diuretic effect.
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