-
公开(公告)号:US20060035911A1
公开(公告)日:2006-02-16
申请号:US11248905
申请日:2005-10-11
申请人: Kenneth Widder , Lauren Otsuki , Howard Dittrich , Scott Thomson , Roland Blantz
发明人: Kenneth Widder , Lauren Otsuki , Howard Dittrich , Scott Thomson , Roland Blantz
IPC分类号: A61K31/549 , A61K31/522
CPC分类号: A61K45/06 , A61K31/405 , A61K31/522 , A61K31/63 , A61K31/635 , A61K2300/00
摘要: Disclosed is a pharmaceutical composition comprising a therapeutically effective amount of KW-3902, or a salt, ester, amide, metabolite, or prodrug thereof, and a non-adenosine modifying diuretic. Also disclosed are methods of inducing a diuretic effect in an animal comprising the step of administering a therapeutically effective amount of KW-3902, or a salt, ester, amide, metabolite, or prodrug thereof, in combination with second pharmaceutical composition capable of inducing a diuretic effect.
-
2.
公开(公告)号:US20050004145A1
公开(公告)日:2005-01-06
申请号:US10830617
申请日:2004-04-23
申请人: Kenneth Widder , Lauren Otsuki , Howard Dittrich , Scott Thomson , Roland Blantz
发明人: Kenneth Widder , Lauren Otsuki , Howard Dittrich , Scott Thomson , Roland Blantz
IPC分类号: A61K31/405 , A61K31/522 , A61K31/63 , A61K31/635 , A61K45/06 , A61P7/10
CPC分类号: A61K45/06 , A61K31/405 , A61K31/522 , A61K31/63 , A61K31/635 , A61K2300/00
摘要: Disclosed is a pharmaceutical composition comprising a therapeutically effective amount of KW-3902, or a salt, ester, amide, metabolite, or prodrug thereof, and a non-adenosine modifying diuretic. Also disclosed are methods of inducing a diuretic effect in an animal comprising the step of administering a therapeutically effective amount of KW-3902, or a salt, ester, amide, metabolite, or prodrug thereof, in combination with second pharmaceutical composition capable of inducing a diuretic effect.
摘要翻译: 公开了包含治疗有效量的KW-3902或其盐,酯,酰胺,代谢物或前药以及非腺苷改性利尿剂的药物组合物。 还公开了在动物中诱导利尿作用的方法,包括施用治疗有效量的KW-3902或其盐,酯,酰胺,代谢物或前药与能够诱导 利尿作用。
-
公开(公告)号:US20060030572A1
公开(公告)日:2006-02-09
申请号:US11248479
申请日:2005-10-11
申请人: Kenneth Widder , Lauren Otsuki , Howard Dittrich , Scott Thomson , Roland Blantz
发明人: Kenneth Widder , Lauren Otsuki , Howard Dittrich , Scott Thomson , Roland Blantz
IPC分类号: A61K31/549 , A61K31/522
CPC分类号: A61K45/06 , A61K31/405 , A61K31/522 , A61K31/63 , A61K31/635 , A61K2300/00
摘要: Disclosed is a pharmaceutical composition comprising a therapeutically effective amount of KW-3902, or a salt, ester, amide, metabolite, or prodrug thereof, and a non-adenosine modifying diuretic. Also disclosed are methods of inducing a diuretic effect in an animal comprising the step of administering a therapeutically effective amount of KW-3902, or a salt, ester, amide, metabolite, or prodrug thereof, in combination with second pharmaceutical composition capable of inducing a diuretic effect.
-
4.
公开(公告)号:US07579331B2
公开(公告)日:2009-08-25
申请号:US10830617
申请日:2004-04-23
IPC分类号: A61K31/70
CPC分类号: A61K45/06 , A61K31/405 , A61K31/522 , A61K31/63 , A61K31/635 , A61K2300/00
摘要: Disclosed is a pharmaceutical composition comprising a therapeutically effective amount of KW-3902, or a salt, ester, amide, metabolite, or prodrug thereof, and a non-adenosine modifying diuretic. Also disclosed are methods of inducing a diuretic effect in an animal comprising the step of administering a therapeutically effective amount of KW-3902, or a salt, ester, amide, metabolite, or prodrug thereof, in combination with second pharmaceutical composition capable of inducing a diuretic effect.
摘要翻译: 公开了包含治疗有效量的KW-3902或其盐,酯,酰胺,代谢物或前药以及非腺苷改性利尿剂的药物组合物。 还公开了在动物中诱导利尿作用的方法,包括施用治疗有效量的KW-3902或其盐,酯,酰胺,代谢物或前药与能够诱导 利尿作用。
-
-
-