发明申请
- 专利标题： Anti-viral nucleosides
- 专利标题（中）： 抗病毒核苷
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申请号： US11208510申请日： 2005-08-22
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公开(公告)号： US20060040890A1公开(公告)日： 2006-02-23
- 发明人: Joseph Martin , Keshab Sarma , David Smith
- 申请人： Joseph Martin , Keshab Sarma , David Smith
- 专利权人： Roche Palo Alto LLC
- 当前专利权人： Roche Palo Alto LLC
- 主分类号： A61K31/7072
- IPC分类号： A61K31/7072 ; C07H19/12
摘要：
4-Amino-1-((2R,3S,4S,5R)-5-azido-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidin-2-one (I:R1=R2=R3=R4=H) and prodrugs thereof are hepatitis C(HCV) polymerase inhibitors. Also disclosed are compositions and methods for inhibiting HCV and treating HCV-mediated diseases, processes for making the compounds and synthetic intermediates employed in the process.
公开/授权文献
- US07378402B2 Anti-viral nucleosides 公开/授权日：2008-05-27
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