发明申请
- 专利标题: Erythropoietin production accelerator
- 专利标题(中): 促红细胞生成素促进剂
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申请号: US10537407申请日: 2003-12-05
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公开(公告)号: US20060040986A1公开(公告)日: 2006-02-23
- 发明人: Shigehiko Imagawa , Takeshi Dol , Masahiro Tamura , Masao Ohkuchi
- 申请人: Shigehiko Imagawa , Takeshi Dol , Masahiro Tamura , Masao Ohkuchi
- 申请人地址: JP Aichi
- 专利权人: Kowa Co., Ltd.
- 当前专利权人: Kowa Co., Ltd.
- 当前专利权人地址: JP Aichi
- 国际申请: PCT/JP03/15589 WO 20031205
- 主分类号: A61K31/4545
- IPC分类号: A61K31/4545 ; A61K31/444 ; A61K31/4439 ; A61K31/40 ; C07D403/02 ; C07D401/14
摘要:
The present invention relates to a preventive or therapeutic agent for pathological conditions caused by reduced production of erythropoietin, or for anemia, or for chronic anemia, renal anemia, aplastic anemia, or pure red cell aplasia, the agent comprising, as an active ingredient, a cyclic amine compound represented by the following formula (1): wherein, R1, R2 and R3 each independently represent a hydrogen atom, a halogen atom, or hydroxy, alkyl, halogen-substituted alkyl, alkoxy, alkylthio, carboxyl, alkoxycarbonyl or alkanoyl group; W1 and W2 each independently represent N or CH; X represents O, NR4, CONR4 or NR4CO; R4 each represents a hydrogen atom, or an alkyl, alkenyl, alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted aralkyl, or substituted or unsubstituted heteroaralkyl group; and l, m and n each represents a number of 0 or 1, or a salt thereof or a solvate thereof.
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