发明申请
US20060046991A1 Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors
有权
对映异构纯氨基杂芳基化合物作为蛋白激酶抑制剂
- 专利标题： Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors
- 专利标题（中）： 对映异构纯氨基杂芳基化合物作为蛋白激酶抑制剂
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申请号： US11212331申请日： 2005-08-26
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公开(公告)号： US20060046991A1公开(公告)日： 2006-03-02
- 发明人: Jingrong Cui , Lee Funk , Lei Jia , Pei-Pei Kung , Jerry Meng , Mitchell Nambu , Mason Pairish , Hong Shen , Michelle Tran-Dube
- 申请人： Jingrong Cui , Lee Funk , Lei Jia , Pei-Pei Kung , Jerry Meng , Mitchell Nambu , Mason Pairish , Hong Shen , Michelle Tran-Dube
- 专利权人： AGOURON PHARMACEUTICALS, INC.
- 当前专利权人： AGOURON PHARMACEUTICALS, INC.
- 主分类号： A61K31/4965
- IPC分类号： A61K31/4965 ; C07D213/72 ; C07D241/20
摘要：
Enantiomerically pure compound of formula 1 are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.