发明申请
- 专利标题： Vaccine composition
- 专利标题（中）： 疫苗组成
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申请号： US10523055申请日： 2003-07-31
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公开(公告)号： US20060057160A1公开(公告)日： 2006-03-16
- 发明人: Ralph Biemans , Philippe Denoel , Christiane Feron , Carine Goraj , Michael Jennings , Jan Poolman , Vincent Weynants
- 申请人： Ralph Biemans , Philippe Denoel , Christiane Feron , Carine Goraj , Michael Jennings , Jan Poolman , Vincent Weynants
- 优先权： GB0218037.0 20020802; GB0218036.2 20020802; GB0218035.4 20020802; GB0218051.1 20020802; GB0220197.8 20020830; GB0220199.4 20020830; GB0225524.8 20021101; GB0225531.3 20021101; GB0230164.6 20021224; GB0230168.7 20021224; GB0230170.3 20021224; GB0305028.3 20030503
- 国际申请： PCT/EP03/08569 WO 20030731
- 主分类号： A61K39/02
- IPC分类号： A61K39/02 ; C12N15/74 ; C12N1/21
摘要：
The present invention relates to the field of neisserial vaccine compositions, their manufacture, and the use of such compositions in medicine. More particularly it relates to processes of making novel engineered meningococcal strains which are less phase variable in terms of their LOS immunotype, and from which novel LOS subunit or meningococcal outer-membrane vesicle (or bleb) vaccines can be derived.
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