A method of producing a membrane-electrode assembly for a fuel cell remarkably enhances the productivity and properties of fuel cell. There are provided in the method a first catalyst layer forming step of spreading a first coating compound over a running substrate to form a first catalyst layer, an electrolyte forming step of spreading a second coating compound over said first catalyst layer while the first catalyst layer is wet to form an electrolyte layer, a drying step of drying the electrolyte layer, and a second catalyst layer forming step of spreading a third coating compound having a noble metal supported thereon over the dried electrolyte layer to form a second catalyst layer.