发明申请
- 专利标题： Imidazo-triazine derivatives as ligands for gaba receptors
- 专利标题（中）： 咪唑并三嗪衍生物作为gaba受体的配体
-
申请号： US10512608申请日： 2003-05-01
-
公开(公告)号： US20060058303A1公开(公告)日： 2006-03-16
- 发明人: Mark Chambers , Simon Goodacre , David Hallett , Robert Maxey , Michael Russell , Leslie Street
- 申请人： Mark Chambers , Simon Goodacre , David Hallett , Robert Maxey , Michael Russell , Leslie Street
- 优先权： GB02101277 20020502
- 国际申请： PCT/GB03/01957 WO 20030501
- 主分类号： A61K31/53
- IPC分类号： A61K31/53 ; C07D487/04
摘要：
A class of imidazo[1,2b][1,2,4]triazine derivatives, substituted at the 7-position by an optionally substituted five-membered or six-membered heteroaromatic ring, being selective ligands for GABAA receptors, in particular having good affinity for the α2 and/or α3 and/or α5 subunit thereof, are accordingly of benefit in the treatment and/or prevention of adverse conditions of the central nervous system, including anxiety, convulsions and cognitive disorders.
公开/授权文献
- US07176203B2 Imidazo-triazine derivatives as ligands for gaba receptors 公开/授权日：2007-02-13
信息查询
