- 专利标题： Antibodies that immunospecifically bind to B lymphocyte stimulator protein
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申请号： US11266444申请日： 2005-11-04
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公开(公告)号： US20060062789A1公开(公告)日： 2006-03-23
- 发明人: Steven Ruben , Steven Barash , Gil Choi , Tristan Vaughan , David Hilbert
- 申请人： Steven Ruben , Steven Barash , Gil Choi , Tristan Vaughan , David Hilbert
- 申请人地址： US MD Rockville GB Cambridge
- 专利权人： Human Genome Sciences, Inc.,Cambridge Antibody Technology, Ltd.
- 当前专利权人： Human Genome Sciences, Inc.,Cambridge Antibody Technology, Ltd.
- 当前专利权人地址： US MD Rockville GB Cambridge
- 主分类号： C07K16/24
- IPC分类号： C07K16/24 ; A61K39/395 ; G01N33/53
摘要：
The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.
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