发明申请
- 专利标题： Treatment of neurological deficits in the striatum or substanta nigra pars compacta
- 专利标题（中）： 治疗纹状体或黑质神经功能缺损
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申请号： US10952064申请日： 2004-09-28
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公开(公告)号： US20060069008A1公开(公告)日： 2006-03-30
- 发明人: Sanjay Mistry , Darin Messina
- 申请人： Sanjay Mistry , Darin Messina
- 主分类号： A61K38/18
- IPC分类号： A61K38/18
摘要：
The present invention is directed to methods of treating neurological deficits resulting from injury or disease to the striatum or substanta nigra pars compacta of a human by administering human recombinant GDF5 to the striatum or substanta nigra pars compacta of a human in amounts effective to induce cell populations having the capacity to differentiate towards a dopaminergic phenotype to in fact differentiate towards a dopaminergic phenotype, and to neurotrophic compositions and matrices suitable for use in such treatments.
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