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1.发明申请公开(公告)号：US20060234376A1
公开(公告)日：2006-10-19
申请号：US11317574
申请日：2005-12-23
申请人： Sanjay Mistry , Darin Messina , Ian Harris , Alexander Harmon , Anthony Kihm , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人： Sanjay Mistry , Darin Messina , Ian Harris , Alexander Harmon , Anthony Kihm , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
IPC分类号： C12N5/08
CPC分类号： A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要： Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of ocular tissue using the postpartum-derived cells are also disclosed.
摘要翻译： 公开了产自产后脐带和胎盘的细胞。 还公开了使用产后来源细胞再生或修复眼组织的药物组合物，装置和方法。
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公开(公告)号：US20050214377A1
公开(公告)日：2005-09-29
申请号：US11081247
申请日：2005-03-16
申请人： Sanjay Mistry , Iksoo Chun , Darin Messina , Anna Gosiewska
发明人： Sanjay Mistry , Iksoo Chun , Darin Messina , Anna Gosiewska
CPC分类号： A61K9/0024 , A61K9/1647 , A61K9/167 , A61K35/12 , A61K35/30 , A61K35/51 , A61K38/1858 , A61K2300/00
摘要： The invention relates to microparticles and compositions containing the microparticles for use in delivering viable cells to specific regions in the body for treatment of diseases in the body, and to methods of treatment of such diseases, where the microparticles include a core containing an effective amount of a biologically active agent distributed there through, and a cell attached to the surface of the core, and where the compositions contain the microparticles and a vehicle for the microparticles.
摘要翻译： 本发明涉及含有用于将活细胞递送到体内特定区域以用于治疗身体疾病的微粒和组合物的微粒和组合物，以及治疗这些疾病的方法，其中微粒包括含有有效量 通过其分布的生物活性剂和附着于芯表面的细胞，组合物含有微粒和微粒载体。
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3.发明申请Treatment of Parkinson's disease and related disorders using postpartum derived cells 有权使用产后衍生细胞治疗帕金森病和相关疾病公开(公告)号：US20060233766A1
公开(公告)日：2006-10-19
申请号：US11315943
申请日：2005-12-22
申请人： Darin Messina , Sanjay Mistry , L.S. Hong , Brian Kramer , Michael Romanko
发明人： Darin Messina , Sanjay Mistry , L.S. Hong , Brian Kramer , Michael Romanko
IPC分类号： A61K35/30
CPC分类号： C12N5/0619 , A61K35/30 , A61K35/44 , C12N2501/11 , C12N2501/115 , C12N2501/119 , C12N2506/03 , A61K2300/00
摘要： Cells derived from postpartum tissue such as the umbilical cord and placenta, pharmaceutical compositions comprising such cells, and methods for using such cells and pharmaceutical compositions to treat patients having a neurodegenerative condition of the substantia nigra or striatum, such as Parkinson's disease, are provided.
摘要翻译： 提供衍生自产后组织如脐带和胎盘的细胞，包含这种细胞的药物组合物，以及使用这些细胞和药物组合物治疗患有黑质或纹状体如神经退行性疾病如帕金森病的患者的方法。
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4.发明申请Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells 有权使用产后衍生细胞治疗中风和其他急性神经变性疾病公开(公告)号：US20060233765A1
公开(公告)日：2006-10-19
申请号：US11315898
申请日：2005-12-22
申请人： Darin Messina , Sanjay Mistry , L. S. Hong , Brian Kramer , Michael Romanko , Anna Gosiewska
发明人： Darin Messina , Sanjay Mistry , L. S. Hong , Brian Kramer , Michael Romanko , Anna Gosiewska
CPC分类号： A61K35/30 , A61K35/12 , A61K35/48 , C12N5/0605 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2533/50 , A61K2300/00
摘要： Cells derived from postpartum tissue such as the umbilical cord and placenta, and methods for their use to regenerate, repair, and improve neural tissue, and to improve behavior and neurological function in stroke patients are disclosed.
摘要翻译： 公开了衍生自产后组织如脐带和胎盘的细胞，以及用于再生，修复和改善神经组织以及改善中风患者的行为和神经功能的方法。
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5.发明申请Cartilage and bone repair and regeneration using postpartum-derived cells 审中-公开使用产后来源的细胞进行软骨和骨修复和再生公开(公告)号：US20060153818A1
公开(公告)日：2006-07-13
申请号：US11321864
申请日：2005-12-29
CPC分类号： A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要： Cells derived from postpartum tissue and methods for their isolation and induction to differentiate to cells of a chondrogenic or osteogenic phenotype are provided by the invention. The invention further provides cultures and compositions of the postpartum-derived cells and products related thereto. The postpartum-derived cells of the invention and products related thereto have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications, for example, in the treatment of bone and cartilage conditions.
摘要翻译： 源自产后组织的细胞及其分离和诱导分化成软骨形成或成骨表型细胞的方法由本发明提供。 本发明进一步提供产后来源细胞的培养物和组合物及其相关的产品。 本发明的产后衍生细胞及其相关产品具有多种用途，包括但不限于研究，诊断和治疗应用，例如用于治疗骨和软骨病症。
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6.发明申请Postpartum cells derived from placental tissue, and methods of making and using the same 有权来自胎盘组织的产后细胞，以及制造和使用胎盘组织的方法公开(公告)号：US20050058631A1
公开(公告)日：2005-03-17
申请号：US10877446
申请日：2004-06-25
申请人： Anthony Kihm , Ian Harris , Sanjay Mistry , Alexander Harmon , Darin Messina , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人： Anthony Kihm , Ian Harris , Sanjay Mistry , Alexander Harmon , Darin Messina , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
CPC分类号： A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要： Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
摘要翻译： 由产后胎盘衍生的细胞及其分离方法由本发明提供。 本发明还提供了胎盘衍生细胞的培养物和组合物。 本发明的胎盘衍生细胞具有许多用途，包括但不限于研究，诊断和治疗应用。
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7.发明申请Postpartum-derived cells for use in treatment of disease of the heart and circulatory system 有权产后来源的细胞用于治疗心脏和循环系统疾病公开(公告)号：US20050058630A1
公开(公告)日：2005-03-17
申请号：US10877445
申请日：2004-06-25
申请人： Ian Harris , Alexander Harmon , Anthony Kihm , Darin Messina , Sanjay Mistry , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人： Ian Harris , Alexander Harmon , Anthony Kihm , Darin Messina , Sanjay Mistry , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
CPC分类号： A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要： Cells derived from postpartum tissue are disclosed along with methods for their therapeutic use in diseases of the heart or circulatory system are disclosed. Cells may be used therapeuticall in either differentiated or undifferentiated forms, in homogenous cultures, or as populations with other cells, and in conjunction with other bioactive factors.
摘要翻译： 公开了衍生自产后组织的细胞以及其在心脏或循环系统疾病中的治疗用途的方法。 细胞可以以分化或未分化的形式，在均匀培养物中，或与其他细胞群体一起使用，并与其它生物活性因子结合使用。
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8.发明申请Postpartum cells derived from umbilical cord tissue, and methods of making and using the same 有权来自脐带组织的产后细胞，以及制造和使用它们的方法公开(公告)号：US20050054098A1
公开(公告)日：2005-03-10
申请号：US10877012
申请日：2004-06-25
申请人： Sanjay Mistry , Anthony Kihm , Ian Harris , Alexander Harmon , Darin Messina , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人： Sanjay Mistry , Anthony Kihm , Ian Harris , Alexander Harmon , Darin Messina , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
CPC分类号： A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要： Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
摘要翻译： 公开了源自人脐带的细胞及其治疗用途的方法。 描述了相对于其细胞表面标志物的细胞的分离技术，培养方法和详细表征，基因表达及其营养因子的分泌。
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9.发明申请公开(公告)号：US20050037491A1
公开(公告)日：2005-02-17
申请号：US10877541
申请日：2004-06-25
申请人： Sanjay Mistry , Darin Messina , Ian Harris , Alexander Harmon , Anthony Kihm , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
发明人： Sanjay Mistry , Darin Messina , Ian Harris , Alexander Harmon , Anthony Kihm , Agnieszka Seyda , Chin-Feng Yi , Anna Gosiewska
CPC分类号： A61K35/51 , A01N1/0226 , A61K35/12 , A61K35/50 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1833 , A61K38/1841 , A61K38/185 , A61K38/1858 , A61K38/1866 , A61K38/1891 , A61K38/19 , A61K38/204 , A61K38/2053 , A61K38/27 , A61K45/06 , C12N5/0605 , C12N5/0606 , C12N5/0607 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/03 , C12N2509/00 , C12N2509/10 , C12N2533/50
摘要： Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of ocular tissue using the postpartum-derived cells are also disclosed.
摘要翻译： 公开了产自产后脐带和胎盘的细胞。 还公开了使用产后来源细胞再生或修复眼组织的药物组合物，装置和方法。
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10.发明申请REPAIR AND REGENERATION OF OCULAR TISSUE USING POSTPARTUM-DERIVED CELLS 有权使用POSTPART-DERIVED细胞修复和再生OCAL组织公开(公告)号：US20100272803A1
公开(公告)日：2010-10-28
申请号：US12054718
申请日：2008-03-25
申请人： Sanjay Mistry , Darin Messina
发明人： Sanjay Mistry , Darin Messina
CPC分类号： A61K35/51 , A61K9/0048 , A61K35/12 , C12N5/0605 , C12N5/0607 , C12N5/0618 , C12N2500/32 , C12N2500/34 , C12N2500/44 , C12N2500/90 , C12N2500/95 , C12N2501/12 , C12N2501/21 , C12N2501/23 , C12N2502/02 , C12N2506/02 , C12N2506/025 , C12N2506/03 , C12N2506/08 , C12N2509/00 , C12N2533/50
摘要： Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of ocular tissue using the postpartum-derived cells are also disclosed.
摘要翻译： 公开了产自产后脐带和胎盘的细胞。 还公开了使用产后来源细胞再生或修复眼组织的药物组合物，装置和方法。
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