发明申请
US20060073496A1 Methods of identifying patients at risk of developing encephalitis following immunotherapy for Alzheimer's disease
审中-公开
鉴定患有阿尔茨海默病免疫治疗后发生脑炎风险的患者的方法
- 专利标题： Methods of identifying patients at risk of developing encephalitis following immunotherapy for Alzheimer's disease
- 专利标题（中）： 鉴定患有阿尔茨海默病免疫治疗后发生脑炎风险的患者的方法
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申请号： US11186236申请日： 2005-07-20
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公开(公告)号： US20060073496A1公开(公告)日： 2006-04-06
- 发明人: Margot O'Toole , Andrew Dorner , Derek Janszen , Donna Slonim , William Mounts , Padmalatha Reddy , Andrew Hill
- 申请人： Margot O'Toole , Andrew Dorner , Derek Janszen , Donna Slonim , William Mounts , Padmalatha Reddy , Andrew Hill
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; G06F19/00
摘要：
The present invention generally relates to a method for an improved treatment for Alzheimer's disease (AD) using immunotherapy, e.g., immunotherapy targeting β amyloid (Aβ), e.g., immunotherapy based on AN1792. In one embodiment, the method allows for predicting an adverse clinical response, and therefore allows for an improved safety profile of AN1792. In another embodiment, the method allows for predicting a favorable clinical response, and therefore allows for an improved efficacy profile of AN1792. The methods of the present invention may be combined to predict a favorable clinical response and the lack of an adverse clinical response.
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