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1.发明申请Methods of identifying patients at risk of developing encephalitis following immunotherapy for Alzheimer's disease 审中-公开鉴定患有阿尔茨海默病免疫治疗后发生脑炎风险的患者的方法公开(公告)号：US20060073496A1
公开(公告)日：2006-04-06
申请号：US11186236
申请日：2005-07-20
申请人： Margot O'Toole , Andrew Dorner , Derek Janszen , Donna Slonim , William Mounts , Padmalatha Reddy , Andrew Hill
发明人： Margot O'Toole , Andrew Dorner , Derek Janszen , Donna Slonim , William Mounts , Padmalatha Reddy , Andrew Hill
CPC分类号： G01N33/5023 , C12Q1/6883 , C12Q2600/106 , C12Q2600/158 , G01N33/5008 , G01N33/5044 , G01N33/6896 , G06Q50/24 , G16B25/00 , G16B40/00 , G16B50/00 , Y02A90/22 , Y02A90/26
摘要： The present invention generally relates to a method for an improved treatment for Alzheimer's disease (AD) using immunotherapy, e.g., immunotherapy targeting β amyloid (Aβ), e.g., immunotherapy based on AN1792. In one embodiment, the method allows for predicting an adverse clinical response, and therefore allows for an improved safety profile of AN1792. In another embodiment, the method allows for predicting a favorable clinical response, and therefore allows for an improved efficacy profile of AN1792. The methods of the present invention may be combined to predict a favorable clinical response and the lack of an adverse clinical response.
摘要翻译： 本发明总体上涉及使用免疫治疗（例如针对β淀粉样蛋白（Abeta）的免疫治疗），例如基于AN1792的免疫治疗来改善阿尔茨海默氏病（AD）治疗的方法。 在一个实施方案中，该方法允许预测不利的临床反应，因此允许改进AN1792的安全性。 在另一个实施方案中，该方法允许预测有利的临床反应，因此允许改进AN1792的功效特征。 本发明的方法可以组合以预测良好的临床反应和缺乏不利的临床反应。
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公开(公告)号：US20200294010A1
公开(公告)日：2020-09-17
申请号：US16892335
申请日：2020-06-04
申请人： Ryan Hardin , Andrew Hill
发明人： Ryan Hardin , Andrew Hill
摘要： A method assigns token requirements to service subscriptions in a service platform, such as a service platform containing entities or a database containing a plurality of said entities. The operator of the service platform establishes customization factors and maintains records reserving data services associated with token requirements for delivery to entities. In addition, customization factors are determined from values representing information associated with objects in a database. Token requirements associated with data services are calculated from one or more formulas utilizing customization factors. Sponsorships associated with the entities can be accepted by the service platform. The service platform can apply credit toward the fulfillment of token requirements. An entity can be provided a data service based on a relationship with a sponsorship such that an entity assigned a subscription having a token requirement fulfilled as a result of applying credit from a sponsorship will receive services related to the subscription.
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公开(公告)号：US10049387B2
公开(公告)日：2018-08-14
申请号：US15694786
申请日：2017-09-02
申请人： Ryan Hardin , Andrew Hill
发明人： Ryan Hardin , Andrew Hill
摘要： Application developers can request to have their applications registered for use with a content delivery platform. The operator of the content delivery platform establishes perimeters defining geographic areas, and maintains records reserving particular areas for delivery of content associated with particular sponsors. Registered applications running on mobile devices can request content from the content delivery platform. Based at least in part on the request, the content delivery platform can identify a target location, which may be the location of the mobile device, or some other location indicated in the request. A mobile device can be provided content based on the relationship of the target location to the geographic areas, so that a registered application running on a mobile device with a target location contained within a geographic area assigned to a particular sponsor will receive content related to that sponsor.
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公开(公告)号：US09710794B2
公开(公告)日：2017-07-18
申请号：US14930200
申请日：2015-11-02
申请人： Ryan Hardin , Andrew Hill
发明人： Ryan Hardin , Andrew Hill
CPC分类号： G06Q20/102 , G06Q20/3825 , G06Q30/0273 , H04L41/06 , H04L67/02
摘要： A method assigns token requirements to service subscriptions in a service platform, such as a service platform containing entities or a database containing a plurality of said entities. The operator of the service platform establishes customization factors and maintains records reserving data services associated with token requirements for delivery to entities. In addition, customization factors are determined from values representing information associated with objects in a database. Token requirements associated with data services are calculated from one or more formulas utilizing customization factors. Sponsorships associated with the entities can be accepted by the service platform. The service platform can apply credit toward the fulfillment of token requirements. An entity can be provided a data service based on a relationship with a sponsorship such that an entity assigned a subscription having a token requirement fulfilled as a result of applying credit from a sponsorship will receive services related to the subscription.
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公开(公告)号：US08977247B2
公开(公告)日：2015-03-10
申请号：US13856392
申请日：2013-04-03
申请人： Ryan Hardin , Andrew Hill
发明人： Ryan Hardin , Andrew Hill
CPC分类号： G06Q30/0261 , G06Q30/02 , G06Q30/0266 , G06Q30/0267 , H04L67/20 , H04M3/42357 , H04M2242/14 , H04W4/02 , H04W4/021 , H04W4/18
摘要： Application developers can request to have their applications registered for use with a content delivery platform. The operator of the content delivery platform establishes perimeters defining geographic areas, and maintains records reserving particular areas for delivery of content associated with particular sponsors. Registered applications running on mobile devices can request content from the content delivery platform. Based at least in part on the request, the content delivery platform can identify a target location, which may be the location of the mobile device, or some other location indicated in the request. A mobile device can be provided content based on the relationship of the target location to the geographic areas, so that a registered application running on a mobile device with a target location contained within a geographic area assigned to a particular sponsor will receive content related to that sponsor.
摘要翻译： 应用程序开发人员可以请求将其应用程序注册到内容传递平台中使用。 内容传送平台的运营商建立了定义地理区域的周界，并且维护记录保留用于传送与特定赞助者相关联的内容的特定区域。 在移动设备上运行的注册应用可以从内容发布平台请求内容。 至少部分地基于该请求，内容传送平台可以识别目标位置，其可以是移动设备的位置，或者请求中指示的某个其他位置。 可以基于目标位置与地理区域的关系来提供移动设备的内容，使得在移动设备上运行的具有目标位置的注册应用包含在分配给特定赞助者的地理区域内的内容将接收与该特定赞助商有关的内容 赞助。
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公开(公告)号：US08437646B2
公开(公告)日：2013-05-07
申请号：US13585879
申请日：2012-08-15
申请人： Nicholas Baxter , Andrew Hill , Andrew Ashwood , Nicholas Gates , Robert Sanders , Andrew Williams
发明人： Nicholas Baxter , Andrew Hill , Andrew Ashwood , Nicholas Gates , Robert Sanders , Andrew Williams
CPC分类号： G03G15/6511 , B41J11/0095 , B41J13/0018 , B65H5/062 , B65H7/12 , B65H2220/09 , B65H2301/44514 , B65H2404/14 , B65H2404/632 , B65H2511/524 , B65H2513/41 , G03G2215/00396 , G03G2215/004 , B65H2220/01 , B65H2220/02 , B65H2220/11
摘要： A paper feed system for use in a printing apparatus that detects multi-feeds and separates all sheets while allowing a single sheet to continue into the machine includes a nip with a drive roller for feeding sheets. A reversible pressure roller downstream of the drive roller is connected to a motor, but idles in the direction of the paper feed in normal operation. When a multi-feed is detected, the motor is turned ON and the reversible pressure roll actuated by a controller. The reversible pressure roller has more friction with the sheet in its contact than the friction between sheets. This drives the sheet in contact backwards.
摘要翻译： 用于在允许单张纸继续进入机器的同时检测多次进给和分离所有片材的打印设备中的进纸系统包括具有用于进给纸张的驱动辊的辊隙。 驱动辊下游的可逆压力辊连接到电动机，但在正常操作中在供纸方向空转。 当检测到多进给时，马达被打开，可逆压力辊由控制器启动。 可逆压力辊与片材在接触时的摩擦力大于片材之间的摩擦力。 这会使纸张向后移动。
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公开(公告)号：US20100279665A1
公开(公告)日：2010-11-04
申请号：US12434094
申请日：2009-05-01
申请人： Ryan Hardin , Andrew Hill
发明人： Ryan Hardin , Andrew Hill
CPC分类号： G06Q30/0261 , G06Q30/02 , G06Q30/0266 , G06Q30/0267 , H04L67/20 , H04M3/42357 , H04M2242/14 , H04W4/02 , H04W4/021 , H04W4/18
摘要： Application developers can request to have their applications registered for use with a content delivery platform. The operator of the content delivery platform establishes perimeters defining geographic areas, and maintains records reserving particular areas for delivery of content associated with particular sponsors. Registered applications running on mobile devices can request content from the content delivery platform. Based at least in part on the request, the content delivery platform can identify a target location, which may be the location of the mobile device, or some other location indicated in the request. A mobile device can be provided content based on the relationship of the target location to the geographic areas, so that a registered application running on a mobile device with a target location contained within a geographic area assigned to a particular sponsor will receive content related to that sponsor.
摘要翻译： 应用程序开发人员可以请求将其应用程序注册到内容传递平台中使用。 内容传送平台的运营商建立了定义地理区域的周界，并且维护记录保留用于传送与特定赞助者相关联的内容的特定区域。 在移动设备上运行的注册应用可以从内容发布平台请求内容。 至少部分地基于该请求，内容传送平台可以识别目标位置，其可以是移动设备的位置，或者请求中指示的某个其他位置。 可以基于目标位置与地理区域的关系来提供移动设备的内容，使得在移动设备上运行的具有目标位置的注册应用包含在分配给特定赞助者的地理区域内的内容将接收与该特定赞助商相关的内容 赞助。
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8.发明申请Faster warm-up, lower energy, and quieter modes for solid ink printers 有权固体墨水打印机更快速的预热，更低的能量和更安静的模式公开(公告)号：US20070103523A1
公开(公告)日：2007-05-10
申请号：US11270214
申请日：2005-11-08
申请人： Trevor Snyder , Amy Bartlett , Bo Wu , Randall Bridgeman , Andrew Hill , Jennifer Miyamoto , Jule Thomas , Donald Titterington , Steven Korol , David Knierim
发明人： Trevor Snyder , Amy Bartlett , Bo Wu , Randall Bridgeman , Andrew Hill , Jennifer Miyamoto , Jule Thomas , Donald Titterington , Steven Korol , David Knierim
IPC分类号： B41J2/175
CPC分类号： B41J2/17593 , B41J2/0057
摘要： A method of operating a printer turns off a support structure heater when the printer enters standby mode. The print head is then moved away from an intermediate transfer surface supported by a support structure. Heat settings used to heat a print head are then varied to heat the print head and the support structure. Another method of operating a printer turns off a support structure heater when the printer enters standby mode and holds a print head adjacent to an intermediate transfer surface while the printer is in standby mode.
摘要翻译： 当打印机进入待机模式时，操作打印机的方法会关闭支撑结构加热器。 然后打印头从支撑结构支撑的中间转印表面移开。 然后改变用于加热打印头的热设置以加热打印头和支撑结构。 当打印机处于待机模式时，当打印机进入待机模式并将打印头保持在中间传送表面附近时，操作打印机的另一种方法会关闭支撑结构加热器。
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公开(公告)号：US20060274305A1
公开(公告)日：2006-12-07
申请号：US11145873
申请日：2005-06-06
申请人： Hwan Jeong , Andrew Hill , Mark Wang
发明人： Hwan Jeong , Andrew Hill , Mark Wang
IPC分类号： G01N21/88
CPC分类号： G01N21/95623
摘要： Serrated Fourier filters and inspection systems are provided. One Fourier filter includes one or more blocking elements configured to block a portion of light from a wafer. The Fourier filter also includes periodic serrations formed on edges of the one or more blocking elements. The periodic serrations define a transition region of the one or more blocking elements. The periodic serrations are configured to vary transmission across the transition region such that variations in the transmission across the transition region are substantially smooth. One inspection system includes a Fourier filter configured as described above and a detector that is configured to detect light transmitted by the Fourier filter. Signals generated by the detector can be used to detect the defects on the wafer.
摘要翻译： 提供锯齿傅立叶滤波器和检测系统。 一个傅立叶滤波器包括被配置为阻挡来自晶片的一部分光的一个或多个阻挡元件。 傅立叶滤波器还包括形成在一个或多个阻挡元件的边缘上的周期性锯齿。 周期性锯齿限定了一个或多个阻挡元件的过渡区域。 周期性锯齿被配置为改变穿过过渡区域的传输，使得跨越过渡区域的透射率的变化基本上是平滑的。 一个检查系统包括如上所述构造的傅里叶滤波器和被配置为检测由傅里叶滤波器发送的光的检测器。 由检测器产生的信号可用于检测晶片上的缺陷。
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公开(公告)号：US5960498A
公开(公告)日：1999-10-05
申请号：US897123
申请日：1997-07-18
CPC分类号： B25F1/003
摘要： A foldable multi-purpose tool includes a pair of jaws and a pair of folding handles and is capable of accepting removable cartridges. In the extended position, the handles operate the jaws. Each removable cartridge contains a number of relatively small tool blades that are preferably selected by functional categories. Various cartridge hold-down and removal mechanisms are also provided.
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