- 专利标题： Antisense modulation of matrix metalloproteinase 1 expression
-
申请号： US11250884申请日： 2005-10-13
-
公开(公告)号： US20060074043A1公开(公告)日： 2006-04-06
- 发明人: Brett Monia , Susan Freier , Sanjay Bhanot , Madeline Butler , Andrew Watt , Jacqueline Wyatt , Brenda Baker , Lex Cowsert , Kenneth Dobie
- 申请人： Brett Monia , Susan Freier , Sanjay Bhanot , Madeline Butler , Andrew Watt , Jacqueline Wyatt , Brenda Baker , Lex Cowsert , Kenneth Dobie
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C07H21/04
摘要：
Antisense compounds, compositions and methods are provided for modulating the expression of matrix metalloproteinase 1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding matrix metalloproteinase 1. Methods of using these compounds for modulation of matrix metalloproteinase 1 expression and for treatment of diseases associated with expression of matrix metalloproteinase 1 are provided.
信息查询
