Invention Application
US20060074231A1 Amino acid-containing compounds and derivatives labeled with halides and method of making
审中-公开
含有氨基酸的化合物和用卤化物标记的衍生物及其制备方法
- Patent Title: Amino acid-containing compounds and derivatives labeled with halides and method of making
- Patent Title (中): 含有氨基酸的化合物和用卤化物标记的衍生物及其制备方法
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Application No.: US10957220Application Date: 2004-10-04
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Publication No.: US20060074231A1Publication Date: 2006-04-06
- Inventor: Tiberiu Siclovan , Faisal Syud , Bruce Johnson
- Applicant: Tiberiu Siclovan , Faisal Syud , Bruce Johnson
- Assignee: General Electric Company
- Current Assignee: General Electric Company
- Main IPC: C07K14/00
- IPC: C07K14/00 ; C07D209/18 ; C07H21/04 ; C07C227/16
Abstract:
A method of labeling amino acid-containing compounds and derivatives thereof with a halide moiety comprises reacting a nucleophilic moiety on such compounds with a halogenated electrophilic compound. Radioactive halide-labeled amino acid-containing compounds can be targeted to diseased sites and provide a means to diagnose and/or treat the disease.
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