发明申请
- 专利标题: Vaccine for feline infectious peritonitis
- 专利标题(中): 猫感染性腹膜炎疫苗
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申请号: US10520333申请日: 2003-07-04
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公开(公告)号: US20060083755A1公开(公告)日: 2006-04-20
- 发明人: Kenji Motokawa , Hajime Kusuhara , Hiroyuki Koyama , Tsutomu Hohdatsu , Setsuo Arai
- 申请人: Kenji Motokawa , Hajime Kusuhara , Hiroyuki Koyama , Tsutomu Hohdatsu , Setsuo Arai
- 申请人地址: JP Tokyo 108-8642
- 专利权人: The Kitasato Institute
- 当前专利权人: The Kitasato Institute
- 当前专利权人地址: JP Tokyo 108-8642
- 优先权: JP2002-196290 20020704
- 国际申请: PCT/JP03/08524 WO 20030704
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; C12Q1/70 ; C12Q1/68 ; A61K39/12
摘要:
FIP vaccines were provided that use an N protein with a specific structure, or a fragment thereof, as an antigen. Preferred antigens of this invention are N proteins derived from a specific type I virus strain (KU-2). Vaccines comprising such an N protein confer preventive effects against a wide range of FIPVs. In addition, the N proteins are very safe because they do not comprise epitopes that enhance infection. Furthermore, preventive effects can be accomplished against type I viruses, which actually cause 70% or more of FIP.
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