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1.发明申请Test Method on Feline Vaccinated with Feline Immunodeficiency Virus Vaccine, and Antigen for Use in the Test 失效用猫免疫缺陷病毒疫苗接种疫苗的试验方法和试验中使用的抗原公开(公告)号：US20100267047A1
公开(公告)日：2010-10-21
申请号：US12670592
申请日：2008-07-25
IPC分类号： G01N33/53 , G01N33/566 , C12N5/07
CPC分类号： C07K16/1045 , G01N33/56988 , G01N2333/155 , G01N2469/20
摘要： Since FIV-vaccinated cats produce antibodies against FIV, distinguishing them from FIV-infected cats is difficult by serological diagnostic methods using FIV and FIV-derived substances. The present invention enables tests for determining the presence or absence of a FIV vaccination history in a cat by detecting antibodies that are produced as a result of vaccination of a cat with an FIV vaccine, but not as a result of FIV infection. Using the methods of the present invention, whether an anti-FIV antibody-positive cat is infected with FIV or has been vaccinated can be conveniently distinguished.
摘要翻译： 由于FIV疫苗接种的猫产生针对FIV的抗体，因此使用FIV和FIV衍生物质的血清学诊断方法难以将其与FIV感染的猫区分开来。 本发明能够通过检测作为FIV疫苗接种猫而不是FIV感染的结果产生的抗体来测定猫中FIV疫苗接种历史的存在或不存在。 使用本发明的方法，可以方便地区分抗FIV抗体阳性的猫是否被FIV感染或已经接种疫苗。
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公开(公告)号：US20060083755A1
公开(公告)日：2006-04-20
申请号：US10520333
申请日：2003-07-04
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/215 , A61K2039/53 , A61K2039/552 , A61K2039/55588 , C12N2710/14143 , C12N2770/20022 , C12N2770/20034 , G01N33/56983
摘要： FIP vaccines were provided that use an N protein with a specific structure, or a fragment thereof, as an antigen. Preferred antigens of this invention are N proteins derived from a specific type I virus strain (KU-2). Vaccines comprising such an N protein confer preventive effects against a wide range of FIPVs. In addition, the N proteins are very safe because they do not comprise epitopes that enhance infection. Furthermore, preventive effects can be accomplished against type I viruses, which actually cause 70% or more of FIP.
摘要翻译： 提供使用具有特定结构的N蛋白或其片段作为抗原的FIP疫苗。 本发明优选的抗原是来源于特异性I型病毒株（KU-2）的N蛋白。 包含这样的N蛋白质的疫苗赋予针对各种FIPV的预防效果。 此外，N蛋白是非常安全的，因为它们不包含增强感染的表位。 此外，可以针对实际引起70％或更多FIP的I型病毒实现预防效果。
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3.发明授权Test method on feline vaccinated with feline immunodeficiency virus vaccine, and antigen for use in the test 失效用猫免疫缺陷病毒疫苗接种疫苗的试验方法和用于试验的抗原公开(公告)号：US08394581B2
公开(公告)日：2013-03-12
申请号：US12670592
申请日：2008-07-25
CPC分类号： C07K16/1045 , G01N33/56988 , G01N2333/155 , G01N2469/20
摘要： Since FIV-vaccinated cats produce antibodies against FIV, distinguishing them from FIV-infected cats is difficult by serological diagnostic methods using FIV and FIV-derived substances. The present invention enables tests for determining the presence or absence of a FIV vaccination history in a cat by detecting antibodies that are produced as a result of vaccination of a cat with an FIV vaccine, but not as a result of FIV infection. Using the methods of the present invention, whether an anti-FIV antibody-positive cat is infected with FIV or has been vaccinated can be conveniently distinguished.
摘要翻译： 由于FIV疫苗接种的猫产生针对FIV的抗体，因此使用FIV和FIV衍生物质的血清学诊断方法难以将其与FIV感染的猫区分开来。 本发明能够通过检测作为FIV疫苗接种猫而不是FIV感染的结果产生的抗体来测定猫中FIV疫苗接种历史的存在或不存在。 使用本发明的方法，可以方便地区分抗FIV抗体阳性的猫是否被FIV感染或已经接种疫苗。
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公开(公告)号：US20120107390A1
公开(公告)日：2012-05-03
申请号：US13284596
申请日：2011-10-28
IPC分类号： A61K9/127 , A61P31/14 , A61P37/04 , A61K39/215
CPC分类号： C07K14/005 , A61K39/00 , A61K39/12 , A61K39/215 , A61K2039/53 , A61K2039/552 , A61K2039/55588 , C12N2710/14143 , C12N2770/20022 , C12N2770/20034 , G01N33/56983
摘要： FIP vaccines were provided that use an N protein with a specific structure, or a fragment thereof, as an antigen. Preferred antigens of this invention are N proteins derived from a specific type I virus strain (KU-2). Vaccines comprising such an N protein confer preventive effects against a wide range of FIPVs. In addition, the N proteins are very safe because they do not comprise epitopes that enhance infection. Furthermore, preventive effects can be accomplished against type I viruses, which actually cause 70% or more of FIP.
摘要翻译： 提供使用具有特定结构的N蛋白或其片段作为抗原的FIP疫苗。 本发明优选的抗原是来源于特异性I型病毒株（KU-2）的N蛋白。 包含这样的N蛋白质的疫苗赋予针对各种FIPV的预防效果。 此外，N蛋白是非常安全的，因为它们不包含增强感染的表位。 此外，可以针对实际引起70％或更多FIP的I型病毒实现预防效果。
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