发明申请
- 专利标题: Antiallergic composition
- 专利标题(中): 抗过敏组合物
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申请号: US10504901申请日: 2004-02-27
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公开(公告)号: US20060088513A1公开(公告)日: 2006-04-27
- 发明人: Sayo Inoue , Toshio Fujii , Daisuke Fujiwara , Akira Saiki , Minoru Takahashi , Koichiro Yamauchi , Masami Gotou , Satoshi Nishida , Keiji Deuchi , Hideyuki Wakabayashi , Toshihiro Komeda
- 申请人: Sayo Inoue , Toshio Fujii , Daisuke Fujiwara , Akira Saiki , Minoru Takahashi , Koichiro Yamauchi , Masami Gotou , Satoshi Nishida , Keiji Deuchi , Hideyuki Wakabayashi , Toshihiro Komeda
- 专利权人: KIRIN BEER KABUSHIKI KAISHA
- 当前专利权人: KIRIN BEER KABUSHIKI KAISHA
- 优先权: JP2003-68943 20030313; JP2003-354277 20031014
- 国际申请: PCT/JP04/02456 WO 20040227
- 主分类号: A61K35/74
- IPC分类号: A61K35/74 ; C12N1/20
摘要:
The object of the present invention is to provide an antiallergic composition useful to prevention/treatment of allergy, its preparation method, and its use as foods or drinks or the like. As for means for solving the object, it is to provide an antiallergic composition comprising as active ingredients the lactic acid bacteria showing equal interleukin 12 production level compared to when Lactobacillus paracasei KW 3110 strain is used as the lactic acid bacteria to be tested, or showing 60% or more of interleukin 12 production level compared to when Lactobacillus paracasei KW 3110 strain is used, and showing less than 50% of interleukin 4 production level of a control wherein the lactic acid bacteria are not added, in case lymphocytes derived from mouse spleen sensitized with ovalbumin are suspended in a medium containing ovalbumin, and cultured by adding the lactic acid bacteria to be tested. The present invention encompasses a method for obtaining the lactic acid bacteria with antiallergic activity being the active ingredients of the antiallergic composition of the present invention, and the use of the antiallergic composition of the present invention to foods and beverages and the like, and further by formulation, the use as antiallergic agent administered orally.
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