发明申请
US20060089355A1 Methods of treating alzheimer's disease using aromatically substituted w-amino-alkanoic acid amides and alkanoic acid diamides
审中-公开
使用芳香取代的w-氨基 - 链烷酸酰胺和链烷酸二酰胺治疗阿尔茨海默病的方法
- 专利标题: Methods of treating alzheimer's disease using aromatically substituted w-amino-alkanoic acid amides and alkanoic acid diamides
- 专利标题(中): 使用芳香取代的w-氨基 - 链烷酸酰胺和链烷酸二酰胺治疗阿尔茨海默病的方法
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申请号: US10517981申请日: 2003-06-11
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公开(公告)号: US20060089355A1公开(公告)日: 2006-04-27
- 发明人: Michel Maillard , Varghese John
- 申请人: Michel Maillard , Varghese John
- 国际申请: PCT/US03/18283 WO 20030611
- 主分类号: A61K31/5377
- IPC分类号: A61K31/5377 ; A61K31/455 ; A61K31/495 ; A61K31/445 ; A61K31/401 ; A61K31/165
摘要:
Disclosed are methods for treating Alzheimer's disease, and other diseases, and/or inhibiting beta-secretase enzyme, and/or inhibiting de-position of A beta peptide in a mammal, by use of compounds of formula (I) wherein the variables R1, R2, R3, R4, R5, X1, and X2 are defined herein.