发明申请
US20060094086A1 Diacylglycerol acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
失效
用于改变多不饱和脂肪酸的二酰基甘油酰基转移酶和含油生物体中的油含量
- 专利标题: Diacylglycerol acyltransferases for alteration of polyunsaturated fatty acids and oil content in oleaginous organisms
- 专利标题(中): 用于改变多不饱和脂肪酸的二酰基甘油酰基转移酶和含油生物体中的油含量
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申请号: US11024544申请日: 2004-12-29
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公开(公告)号: US20060094086A1公开(公告)日: 2006-05-04
- 发明人: Narendra Yadav , Zhixiong Xue , Hongxiang Zhang
- 申请人: Narendra Yadav , Zhixiong Xue , Hongxiang Zhang
- 主分类号: C12P7/64
- IPC分类号: C12P7/64 ; C12P21/06 ; C07H21/04 ; C12N9/10 ; C12N1/18 ; C12N15/74
摘要:
Acyltransferases are provided, suitable for use in the manufacture of microbial oils enriched in omega fatty acids in oleaginous yeast (e.g., Yarrowia lipolytica). Specifically, genes encoding diacylglycerol acyltransferase (DGAT1) have been isolated from Y. lipolytica and Mortierella alpina. These genes encode enzymes that participate in the terminal step in oil biosynthesis in yeast. Each is expected to play a key role in altering the quantity of polyunsaturated fatty acids produced in oils of oleaginous yeasts.
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