发明申请
US20060094967A1 Method and apparatus to provide diagnostic index and therapy regulated by subject's autonomic nervous system
有权
提供受试者自主神经系统调节的诊断指标和治疗的方法和装置
- 专利标题: Method and apparatus to provide diagnostic index and therapy regulated by subject's autonomic nervous system
- 专利标题(中): 提供受试者自主神经系统调节的诊断指标和治疗的方法和装置
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申请号: US10977073申请日: 2004-10-29
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公开(公告)号: US20060094967A1公开(公告)日: 2006-05-04
- 发明人: Tommy Bennett , Edwin Duffin , Robert Taepke , Barbro Kjellstrom
- 申请人: Tommy Bennett , Edwin Duffin , Robert Taepke , Barbro Kjellstrom
- 主分类号: A61B5/02
- IPC分类号: A61B5/02
摘要:
A system and method are provided for determining an index of autonomic nervous system (ANS) or sympathetic nervous system (SNS) activity for use in patient monitoring or therapy delivery control. An ANS or SNS index is calculated as a function of multiple monitored physiological variables that strongly correlate to changes in autonomic or sympathetic tone. These ANS-influenced variables are derived from selected hemodynamic and/or electrical signals and may include variables relating to any of: the maximum rate of pressure rise (dP/dtmax), the maximum rate of pressure decline (dP/dtmin), pulse pressure (PP), pre-ejection time interval (PEI) and/or systolic time interval (STI), heart rate (HR), heart rate variability (HRV), and baro-reflex gain. Changes in the ANS or SNS index may be used to automatically adjust a device delivered therapy.