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    Method and apparatus for continuous pulse contour cardiac output
    1.
    发明申请
    Method and apparatus for continuous pulse contour cardiac output 审中-公开

    公开(公告)号：US20060167361A1

    公开(公告)日：2006-07-27

    申请号：US11045573

    申请日：2005-01-27

    申请人： Tommy Bennett ,  Robert Taepke ,  Barbro Kjellstrom

    发明人： Tommy Bennett ,  Robert Taepke ,  Barbro Kjellstrom

    IPC分类号： A61B5/02

    CPC分类号： A61B5/02028 ,  A61B5/021 ,  A61B5/02108 ,  A61B5/029 ,  A61B5/0456

    摘要： A system and method are provided for sensing cardiac electrogram (EGM) signals and ventricular pressure signals and for using the sensed EGM and sensed pressure signals for estimating stroke volume (SV). A measure of cardiac output can be computed from the estimated SV and a heart rate determined from the EGM signals. The sensed ventricular pressure signal and the sensed EGM signal are used to derive landmark points such as an estimated pulmonary diastolic pressure, a mean pulmonary artery pressure, a peak right ventricular pressure (RVP), and various time intervals used in computing an area or a pulse contour integral. The pulse contour integral is used to estimate SV. The estimated pulmonary diastolic pressure, mean pulmonary artery pressure and CO computed from the estimated SV can be used to compute a pulmonary vascular resistance.

    Method and apparatus to provide diagnostic index and therapy regulated by subject's autonomic nervous system
    3.
    发明申请
    Method and apparatus to provide diagnostic index and therapy regulated by subject's autonomic nervous system 有权
    提供受试者自主神经系统调节的诊断指标和治疗的方法和装置

    公开(公告)号：US20060094967A1

    公开(公告)日：2006-05-04

    申请号：US10977073

    申请日：2004-10-29

    申请人： Tommy Bennett ,  Edwin Duffin ,  Robert Taepke ,  Barbro Kjellstrom

    发明人： Tommy Bennett ,  Edwin Duffin ,  Robert Taepke ,  Barbro Kjellstrom

    IPC分类号： A61B5/02

    CPC分类号： A61B5/0205 ,  A61B5/4035 ,  A61B5/7239 ,  A61N1/36535 ,  A61N1/36578 ,  A61N1/36585 ,  A61N1/36592 ,  A61N1/3702

    摘要： A system and method are provided for determining an index of autonomic nervous system (ANS) or sympathetic nervous system (SNS) activity for use in patient monitoring or therapy delivery control. An ANS or SNS index is calculated as a function of multiple monitored physiological variables that strongly correlate to changes in autonomic or sympathetic tone. These ANS-influenced variables are derived from selected hemodynamic and/or electrical signals and may include variables relating to any of: the maximum rate of pressure rise (dP/dtmax), the maximum rate of pressure decline (dP/dtmin), pulse pressure (PP), pre-ejection time interval (PEI) and/or systolic time interval (STI), heart rate (HR), heart rate variability (HRV), and baro-reflex gain. Changes in the ANS or SNS index may be used to automatically adjust a device delivered therapy.

    摘要翻译： 提供了一种用于确定用于患者监测或治疗递送控制的自主神经系统（ANS）或交感神经系统（SNS）活动指数的系统和方法。 ANS或SNS指数被计算为与自主神经或交感神经紧张度变化密切相关的多个被监测的生理变量的函数。 这些受ANS影响的变量来自选定的血流动力学和/或电信号，并且可以包括与以下任何相关的变量：压力上升的最大速率（dP / dt最大值），最大压力下降速率 （dP / dt分钟），脉压（PP），预喷射时间间隔（PEI）和/或收缩时间间隔（STI），心率（HR），心率变异性（HRV） ，以及压力反射增益。 可以使用ANS或SNS指数的变化来自动调整设备传递的治疗。