发明申请
US20060106202A1 Peripheral-type benzodiazepine receptor associated proteins, cloning, expression and methods of use
审中-公开
外周型苯二氮卓受体相关蛋白，克隆，表达及使用方法
- 专利标题： Peripheral-type benzodiazepine receptor associated proteins, cloning, expression and methods of use
- 专利标题（中）： 外周型苯二氮卓受体相关蛋白，克隆，表达及使用方法
-
申请号： US11331940申请日： 2006-01-13
-
公开(公告)号： US20060106202A1公开(公告)日： 2006-05-18
- 发明人: Vassilios Papadopoulos , Hua Li
- 申请人： Vassilios Papadopoulos , Hua Li
- 专利权人： Georgetown University
- 当前专利权人： Georgetown University
- 主分类号： C07K14/705
- IPC分类号： C07K14/705 ; C07K16/28 ; C12Q1/68 ; G01N33/53 ; C07H21/04 ; C12P21/06 ; A61K39/395
摘要：
The present invention relates to nucleic acids encoding PBR-associated proteins (PAPs) and methods for use in producing PAPs and methods of using PAPs. In this study we have identified proteins (PAPs) that interact with PBR protein by a yeast two-hybrid system. We used PBR as bait to screen a mouse testis cDNA library. Five clones were isolated based on their ability to interact with PBR. These proteins may be involved in the regulation of the function of PBR, serving as an endogenous ligand or allosteric modulator of the receptor.
信息查询
