DNA encoding peripheral-type benzodiazipine receptor associated protein 7 and applications or methods of use
    1.
    发明授权
    DNA encoding peripheral-type benzodiazipine receptor associated protein 7 and applications or methods of use 失效
    编码外周型苯并二氮嗪受体相关蛋白的DNA 7及应用或使用方法

    公开(公告)号:US07056694B1

    公开(公告)日:2006-06-06

    申请号:US09762594

    申请日:1999-08-11

    CPC分类号: C07K14/47

    摘要: The present invention relates to nucleic acids encoding peripheral-type benzodiazepine receptor (PBR)-associated proteins (PAPs), and nucleic acids that hybridize or are variant of nucleic acids encoding the peripheral-type benzodiazepine receptor (PBR)-associated proteins (PAPs), which are capable of encoding proteins that regulate the function of PBRs affecting both steroid biosynthesis and mediating cholesterol delivery as well as other PBR-mediated functions.

    摘要翻译: 本发明涉及编码外周型苯并二氮杂受体(PBR)相关蛋白(PAP)的核酸和与编码外周型苯并二氮杂受体(PBR)相关蛋白(PAP))的核酸杂交或变异的核酸, ,其能够编码调节影响类固醇生物合成和介导胆固醇递送以及其他PBR介导的功能的PBR功能的蛋白质。

    Peripheral-type benzodiazepine receptor associated proteins, cloning, expression and methods of use
    2.
    发明申请
    Peripheral-type benzodiazepine receptor associated proteins, cloning, expression and methods of use 审中-公开
    外周型苯二氮卓受体相关蛋白,克隆,表达及使用方法

    公开(公告)号:US20060106202A1

    公开(公告)日:2006-05-18

    申请号:US11331940

    申请日:2006-01-13

    CPC分类号: C07K14/705 A61K38/00

    摘要: The present invention relates to nucleic acids encoding PBR-associated proteins (PAPs) and methods for use in producing PAPs and methods of using PAPs. In this study we have identified proteins (PAPs) that interact with PBR protein by a yeast two-hybrid system. We used PBR as bait to screen a mouse testis cDNA library. Five clones were isolated based on their ability to interact with PBR. These proteins may be involved in the regulation of the function of PBR, serving as an endogenous ligand or allosteric modulator of the receptor.

    摘要翻译: 本发明涉及编码PBR相关蛋白(PAP)的核酸和用于产生PAP的方法和使用PAP的方法。 在这项研究中,我们已经确定了通过酵母双杂交系统与PBR蛋白质相互作用的蛋白质(PAP)。 我们使用PBR作为诱饵筛选小鼠睾丸cDNA文库。 基于与PBR相互作用的能力分离出5个克隆。 这些蛋白质可能参与调节PBR的功能,作为受体的内源性配体或变构调节剂。

    Method of adjusting speed and/or routing of a table movement plan and a lithographic apparatus
    5.
    发明授权
    Method of adjusting speed and/or routing of a table movement plan and a lithographic apparatus 有权
    调整台面移动平面图和光刻设备的速度和/或路线的方法

    公开(公告)号:US09329491B2

    公开(公告)日:2016-05-03

    申请号:US13168177

    申请日:2011-06-24

    IPC分类号: G03B27/52 G03F7/20

    摘要: A method of adjusting speed and/or routing of a part of a movement plan of a table under an immersion fluid supply system of a lithographic apparatus. The method includes splitting the movement plan of the table into a plurality of discrete movements; determining a risk of a bubble of a size greater than a certain size being present in immersion fluid through which a patterned beam of the lithographic apparatus will pass during a certain discrete movement by determining whether the immersion fluid supply system passes over a position at which immersion fluid leaked from the immersion fluid supply system is present; and adjusting the speed and/or routing of a part of the movement plan corresponding to (i) a discrete movement earlier than a discrete movement for which the risk of a bubble is determined, and/or (ii) a discrete movement for which the risk of a bubble is determined.

    摘要翻译: 一种在光刻设备的浸没液体供应系统下调整桌子的运动计划的一部分的速度和/或路线的方法。 该方法包括将表的运动计划分成多个离散运动; 确定存在于浸没流体中的尺寸大于一定尺寸的气泡的风险,通过该浸入流体中的光刻设备的图案化束将在特定离散运动期间通过该气泡通过确定浸没流体供应系统是否经过浸没的位置 存在从浸没液体供应系统泄漏的液体; 以及调整所述运动计划的一部分的速度和/或路线,其对应于(i)比确定气泡风险的离散运动更早的离散运动,和/或(ii)离散运动, 确定泡沫的风险。

    Predicting keyword monetization
    7.
    发明授权
    Predicting keyword monetization 有权
    预测关键字营利

    公开(公告)号:US08682839B2

    公开(公告)日:2014-03-25

    申请号:US12131125

    申请日:2008-06-02

    IPC分类号: G06F17/30 G06Q40/00

    摘要: Embodiments of the claimed subject matter provide a method and system for predicting bidding keyword monetization. The claimed subject matter provides a method and system with which the value of a keyword for the purpose of relevant online advertisement may be evaluated according to various metrics to determine a bidding landscape for use in advertising campaigns. The value of the keyword considers certain attributes related to the monetization of the keyword.One embodiment of the claimed subject matter is implemented as a method for predicting keyword monetization for one or more keyword-advertisement relationships. Historical data for the one or more keyword-advertisement relationships is referenced and used to generate a global model of the one or more keyword-advertisement relationship. The relationships are then evaluated according to a time-series analysis, which parses the data from the historical data and the global model to create predictions for the keyword monetization according to the keyword-advertisement relationships.

    摘要翻译: 所要求保护的主题的实施例提供了用于预测投标关键字货币化的方法和系统。 所要求保护的主题提供了一种方法和系统,其中可以根据各种度量来评估用于相关在线广告的关键字的价值,以确定用于广告活动的投标景观。 该关键字的值考虑与关键字获利相关的特定属性。 所要求保护的主题的一个实施例被实现为用于预测一个或多个关键字 - 广告关系的关键字获利的方法。 引用一个或多个关键字 - 广告关系的历史数据,并用于生成一个或多个关键字 - 广告关系的全局模型。 然后根据时间序列分析来评估关系,该时间序列分析从历史数据和全球模型中分析数据,以根据关键字 - 广告关系创建关键字营利的预测。

    Non-disruptive failover of RDMA connection
    8.
    发明授权
    Non-disruptive failover of RDMA connection 有权
    RDMA连接的无中断故障切换

    公开(公告)号:US08627136B2

    公开(公告)日:2014-01-07

    申请号:US12978866

    申请日:2010-12-27

    IPC分类号: G06F11/00

    摘要: A novel RDMA connection failover technique that minimizes disruption to upper subsystem modules (executed on a computer node), which create requests for data transfer. A new failover virtual layer performs failover of an RDMA connection in error so that the upper subsystem that created a request does not have knowledge of an error (which is recoverable in software and hardware), or of a failure on the RDMA connection due to the error. Since the upper subsystem does not have knowledge of a failure on the RDMA connection or of a performed failover of the RDMA connection, the upper subsystem continues providing requests to the failover virtual layer without interruption, thereby minimizing downtime of the data transfer activity.

    摘要翻译: 一种新颖的RDMA连接故障切换技术,可最大限度地减少上层子系统模块(在计算机节点上执行)的干扰,从而创建数据传输请求。 新的故障转移虚拟层错误地执行RDMA连接的故障转移,以便创建请求的上级子系统不知道错误(可在软件和硬件中恢复)或RDMA连接发生故障,因为 错误。 由于上级子系统不知道RDMA连接上的故障或RDMA连接的已执行故障转移,上级子系统会继续向故障转移虚拟层提供请求,而不会中断,从而最大限度地减少数据传输活动的停机时间。

    Method of producing fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether
    9.
    发明授权
    Method of producing fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether 有权
    氟甲基1,1,1,3,3,3-六氟异丙醚的制备方法

    公开(公告)号:US08530704B2

    公开(公告)日:2013-09-10

    申请号:US13123190

    申请日:2009-08-25

    申请人: Xu Weiguo Hua Li

    发明人: Xu Weiguo Hua Li

    IPC分类号: C07C43/00

    CPC分类号: C07C41/16 C07C43/123

    摘要: The present invention provides a preparation method of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether by reacting CH2FX with 1,1,1,3,3,3-hexafluoroisopropanol in the presence of acid-binding agent. The reaction can be also preformed in the presence of solvent and/or phase-transfer catalyst. The present method has the advantages of simple reaction, manageable control condition, high material conversion and product yield, and the product can be easily separated. The obtained fluoromethyl 1,1,1,3,3,3-hexafluoroisoprophyl ether can be used as a safe inhalation anesthetics.

    摘要翻译: 本发明提供了在酸结合剂存在下使CH 2 FX与1,1,1,3,3,3-六氟异丙醇反应的氟甲基1,1,1,3,3,3-六氟异丙醚的制备方法。 反应也可以在溶剂和/或相转移催化剂的存在下进行。 本发明方法反应简单,控制条件可控,物料转化率高,产品收率高,产品易于分离。 得到的氟甲基1,1,1,3,3,3-六氟异丙醚可用作安全吸入麻醉剂。

    FRAUD DETECTION BASED ON EFFICIENT FREQUENT-BEHAVIOR SORTED LISTS
    10.
    发明申请
    FRAUD DETECTION BASED ON EFFICIENT FREQUENT-BEHAVIOR SORTED LISTS 有权
    基于有效的行为异常行为的欺诈检测

    公开(公告)号:US20120101937A1

    公开(公告)日:2012-04-26

    申请号:US13340469

    申请日:2011-12-29

    IPC分类号: G06Q40/00

    摘要: A computerized method for detecting fraud includes obtaining frequency information on entities in transaction data for at least one individual account, converting frequency information to a frequency variable, and predicting whether an activity is fraudulent in response to the frequency variable. In some embodiments, the frequency variable is used with at least one other variable to predict fraudulent activity.

    摘要翻译: 用于检测欺诈的计算机化方法包括:获得关于至少一个单独帐户的交易数据中的实体的频率信息,将频率信息转换为频率变量,以及响应于所述频率变量来预测活动是否是欺诈性的。 在一些实施例中,频率变量与至少一个其他变量一起使用以预测欺诈活动。