发明申请
- 专利标题: Methods for preventing and treating alzheimer's disease
- 专利标题(中): 预防和治疗阿尔茨海默病的方法
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申请号: US10540551申请日: 2004-01-13
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公开(公告)号: US20060111301A1公开(公告)日: 2006-05-25
- 发明人: Frank Mattner
- 申请人: Frank Mattner
- 优先权: ATA36/2003 20030114; ATA1464/2003 20030917
- 国际申请: PCT/EP04/00162 WO 20040113
- 主分类号: A61K38/08
- IPC分类号: A61K38/08
摘要:
The invention relates to the use of a compound comprising the following amino acid sequence X1X2X3X4X5X6, wherein X1 is an amino acid, except of C, X2 is an amino acid, except of C, X3 is an amino acid, except of C, X4 is an amino acid, except of C, X5 is an amino acid, except of C, X6 is an amino acid, except of C, and wherein X1X2X3X4X5X6 is not DAEFRH, said compound having a binding capacity to an antibody being specific for the natural N-terminal Aβ42 sequence DAEFRH, and 5-mers thereof having a binding capacity to said antibody being specific for the natural N-terminal Aβ42 sequence DAEFRH, for the preparation of a vaccine for Alzheimer's disease.
公开/授权文献
- US07732568B2 Methods for preventing and treating Alzheimer's disease 公开/授权日:2010-06-08