发明申请
US20060111310A1 Composition comprising triterpene saponins and compounds with angeloyl functional group, methods for preparing same and uses thereof 审中-公开
包含三萜皂苷和具有阴离子官能团的化合物的组合物,其制备方法及其应用

  • 专利标题: Composition comprising triterpene saponins and compounds with angeloyl functional group, methods for preparing same and uses thereof
  • 专利标题(中): 包含三萜皂苷和具有阴离子官能团的化合物的组合物,其制备方法及其应用
  • 申请号: US11267523
    申请日: 2005-11-04
  • 公开(公告)号: US20060111310A1
    公开(公告)日: 2006-05-25
  • 发明人: Pui-Kwong ChanMay MakYun Wang
  • 申请人: Pui-Kwong ChanMay MakYun Wang
  • 主分类号: C07H15/24
  • IPC分类号: C07H15/24 A61K31/704
Composition comprising triterpene saponins and compounds with angeloyl functional group, methods for preparing same and uses thereof
摘要:
This invention provides a compound comprising a triterpenoidal saponin, triterpenoid, triterpenoidal compound or sapongenin, comprising at least two side groups selected from the group consisting of: angeloyl groups, tigloyl groups and senecioyl groups, wherein the side groups are attached to carbon 21, 22 or/and 28 of triterpenoidal saponin, triterpenoid, triterpenoidal compound or sapongenin backbone. This invention provides a composition for inhibiting tumor cell growth, comprising an appropriate amount of a triterpenoidal saponin, triterpenoid, triterpenoidal compound or sapongenin, wherein the triterpenoidal saponin, triterpenoid, triterpenoidal compound or sapongenin comprises any two side groups selected from the group consisting of: angeloyl groups, tigloyl groups and senecioyl groups, wherein the side groups are attached to carbon 21, 22 or/and 28 of triterpenoidal saponin, triterpenoid, triterpenoidal compound or sapongenin backbone.
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