发明申请
- 专利标题： Materials and methods for treating hypercholesterolemia
- 专利标题（中）： 治疗高胆固醇血症的材料和方法
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申请号： US11220364申请日： 2005-09-06
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公开(公告)号： US20060116418A1公开(公告)日： 2006-06-01
- 发明人: Pascal Druzgala , Xiaoming Zhang , Jurg Pfister
- 申请人： Pascal Druzgala , Xiaoming Zhang , Jurg Pfister
- 申请人地址： US CA Fremont
- 专利权人： Aryx Therapeutics, Inc.
- 当前专利权人： Aryx Therapeutics, Inc.
- 当前专利权人地址： US CA Fremont
- 主分类号： A61K31/405
- IPC分类号： A61K31/405 ; C07D209/18
摘要：
The subject invention provides novel HMG-CoA-reductase inhibitors. In a preferred embodiment, the HMG-CoA reductase inhibitors of the subject invention can be deactivated to a primary inactive metabolite by hydrolytic enzymes. Compounds of the present invention can be advantageously used to treat patients suffering hypercholesterolemia.
公开/授权文献
- US07384973B2 Materials and methods for treating hypercholesterolemia 公开/授权日：2008-06-10
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