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发明申请
US20060127420A1 Paclitaxel composition for the intravesical treatment of bladder tumor and preparation method thereof 审中-公开
用于膀胱肿瘤膀胱内治疗的紫杉醇组合物及其制备方法

Paclitaxel composition for the intravesical treatment of bladder tumor and preparation method thereof
摘要：
The present invention relates to a paclitaxel composition and the preparation methods thereof for the treatment of bladder cancer wherein said paclitaxel composition comprises 4˜90% by weight of at least one selected from the monoglycerides, 0.01˜90% by weight of at least one oil, 0.01˜90% by weight of at least one emulsifier and 0.01˜20% by weight of paclitaxel. The composition of the present invention can treat bladder cancer effectively since the composition solubilizes paclitaxel, does not form aggregates, adsorbs well on the bladder wall and penetrates into the muscle layer of the bladder.
摘要（中）：

本发明涉及紫杉醇组合物及其治疗膀胱癌的制备方法，其中所述紫杉醇组合物包含4〜90重量％的选自单酸甘油酯，0.01〜90重量％的至少一种油 ，0.01〜90重量％的至少一种乳化剂和0.01〜20重量％的紫杉醇。 本发明的组合物可以有效治疗膀胱癌，因为组合物溶解紫杉醇，不形成聚集体，在膀胱壁上很好地吸附并渗入膀胱的肌肉层。

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