发明申请
- 专利标题: Methods for inhibiting Stat3 signaling in immune cells
- 专利标题(中): 抑制免疫细胞Stat3信号传导的方法
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申请号: US11300619申请日: 2005-12-14
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公开(公告)号: US20060127502A1公开(公告)日: 2006-06-15
- 发明人: Hua Yu , Richard Jove , Marcin Kortylewski , Drew Pardoll
- 申请人: Hua Yu , Richard Jove , Marcin Kortylewski , Drew Pardoll
- 申请人地址: US FL Tampa US MD Baltimore
- 专利权人: University of South Florida,The Johns Hopkins University
- 当前专利权人: University of South Florida,The Johns Hopkins University
- 当前专利权人地址: US FL Tampa US MD Baltimore
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; A61K33/24 ; A61K31/28 ; A61K31/7072 ; A61K31/7076
摘要:
Methods of enhancing antitumor activity of an immune cell comprising contacting the immune cell with a Stat3 inhibitor are described. Also described are methods of killing a tumor cell or inhibiting tumor growth in a subject comprising contacting an immune cell of the subject with a Stat3 inhibitor.
公开/授权文献
- US07951374B2 Methods for inhibiting STAT3 signaling in immune cells 公开/授权日:2011-05-31
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