发明申请
US20060128667A1 Hydroxyphosphonates and phosphonophosphates as apolipoprotein e modulators
审中-公开
羟磷酸酯和膦酸磷酸酯作为载脂蛋白e调节剂
- 专利标题： Hydroxyphosphonates and phosphonophosphates as apolipoprotein e modulators
- 专利标题（中）： 羟磷酸酯和膦酸磷酸酯作为载脂蛋白e调节剂
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申请号： US10513553申请日： 2003-05-09
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公开(公告)号： US20060128667A1公开(公告)日： 2006-06-15
- 发明人: Imber Montes , Hieu Phan , Lan Nguyen , Emanuele Burattini , Eric Neisor , Anne Perez , Jean Luc Thuillard , Yves Guvon-Gellin , Craig Bentzen
- 申请人： Imber Montes , Hieu Phan , Lan Nguyen , Emanuele Burattini , Eric Neisor , Anne Perez , Jean Luc Thuillard , Yves Guvon-Gellin , Craig Bentzen
- 国际申请： PCT/US03/14728 WO 20030509
- 主分类号： A61K31/675
- IPC分类号： A61K31/675 ; C07F9/547
摘要：
The present invention relates to the novel hydroxyphosphonates and phosphonophosphates and the methods of their use to modulate apolipoprotein E levels and the use of such compounds in therapy, including cardiovascular and neurological disease states.