发明申请
- 专利标题: Rapamycin derivatives and the uses thereof in the treatment of neurological disorders
- 专利标题(中): 雷帕霉素衍生物及其用于治疗神经障碍的用途
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申请号: US11300941申请日: 2005-12-15
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公开(公告)号: US20060135550A1公开(公告)日: 2006-06-22
- 发明人: Edmund Graziani , Kevin Pong , Jerauld Skotnicki
- 申请人: Edmund Graziani , Kevin Pong , Jerauld Skotnicki
- 申请人地址: US NJ Madison
- 专利权人: Wyeth
- 当前专利权人: Wyeth
- 当前专利权人地址: US NJ Madison
- 主分类号: C07D491/14
- IPC分类号: C07D491/14 ; A61K31/4745
摘要:
The present invention provides compounds of the following structure, wherein R1-R9, R15, and n are defined herein. These compounds are useful in treating neurological disorders or complications due to stroke or head injury, and as neuroprotective and neuroregenerative agents.