The invention relates to a heavy vehicle, such as a transport vehicle or a “civil engineering” vehicle, of a mass greater than 500 metric tons, fitted with tires of radial structure of a diameter greater than three meters fifty, and comprising a front axle provided with at least two tires and at least one rear axle comprising at least two tires and by which is transmitted at least part of the motive power. According to the invention, at least one of the axles comprises at least four tires associated in pairs symmetrically on either side of the axle, two associated tires having different axial widths.