Invention Application
US20060140930A1 Promotion of central nervous system remyelination using monoclonal autoantibodies
审中-公开
使用单克隆抗体来促进中枢神经系统髓鞘再生
- Patent Title: Promotion of central nervous system remyelination using monoclonal autoantibodies
- Patent Title (中): 使用单克隆抗体来促进中枢神经系统髓鞘再生
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Application No.: US11224664Application Date: 2005-09-12
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Publication No.: US20060140930A1Publication Date: 2006-06-29
- Inventor: Moses Rodriguez , David Miller , Kunihiko Asakura
- Applicant: Moses Rodriguez , David Miller , Kunihiko Asakura
- Assignee: Mayo Foundation for Medical Research
- Current Assignee: Mayo Foundation for Medical Research
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
Monoclonal IgM antibodies which promote central nervous system remyelination when given to a mammal afflicted with a demyelinating disease are disclosed. These antibodies show multi-organ autoreactivity, and recognize both surface and cytoplasmic determinants on glial cells.
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